Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 2838424..2839085 Replicon chromosome
Accession NZ_CP049791
Organism Ralstonia solanacearum strain 203

Toxin (Protein)


Gene name vapC Uniprot ID A0A9E7Z845
Locus tag G7947_RS13070 Protein ID WP_016727753.1
Coordinates 2838672..2839085 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A9E7Z6P3
Locus tag G7947_RS13065 Protein ID WP_019717749.1
Coordinates 2838424..2838675 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G7947_RS13040 2834073..2834789 + 717 WP_049800424.1 Crp/Fnr family transcriptional regulator -
G7947_RS25780 2835464..2835802 - 339 WP_016727784.1 glycine zipper 2TM domain-containing protein -
G7947_RS13050 2836076..2836291 + 216 WP_071615547.1 hypothetical protein -
G7947_RS13055 2836445..2836677 - 233 Protein_2538 hypothetical protein -
G7947_RS13060 2837274..2838149 + 876 WP_049800423.1 hypothetical protein -
G7947_RS13065 2838424..2838675 + 252 WP_019717749.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
G7947_RS13070 2838672..2839085 + 414 WP_016727753.1 type II toxin-antitoxin system VapC family toxin Toxin
G7947_RS13075 2839157..2840179 - 1023 WP_020425162.1 DNA cytosine methyltransferase -
G7947_RS13080 2840803..2841090 + 288 WP_089190399.1 H-NS histone family protein -
G7947_RS13085 2841133..2841777 - 645 WP_089190400.1 hypothetical protein -
G7947_RS13090 2841752..2841973 - 222 WP_089190401.1 hypothetical protein -
G7947_RS13095 2841970..2842359 - 390 WP_089190402.1 hypothetical protein -
G7947_RS13100 2842520..2843767 + 1248 WP_081365215.1 tyrosine-type recombinase/integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-124)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15586.89 Da        Isoelectric Point: 6.2337

>T151602 WP_016727753.1 NZ_CP049791:2838672-2839085 [Ralstonia solanacearum]
MSYLIDTNVLSELRRKAPDARVVAWMQDRPRQSLYLSVLTLGEIRKGIERLDDAARRQHLIDWLEVELPNYFLGRLLDID
AHTADRWGRLMSSAGRPLPAIDGLLAATALQHDLTLVTRNTKDFAGLDVQLINPWEA

Download         Length: 414 bp

>T151602 NZ_CP065615:1476007-1476114 [Escherichia coli]
ATGACGCTCGCGAAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9305.49 Da        Isoelectric Point: 5.0774

>AT151602 WP_019717749.1 NZ_CP049791:2838424-2838675 [Ralstonia solanacearum]
MQSWQMQAAKARFSDVVKRAADDGPQEITVHGRPVAVVISRALFDRLSGGGESLVSFMRQSPLADQDDVVFERERSLPRE
VEF

Download         Length: 252 bp

>AT151602 NZ_CP065615:c1475954-1475893 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References