151571

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 607989..609025 Replicon chromosome
Accession NZ_CP049786
Organism Leclercia sp. 29361

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag G7090_RS02900 Protein ID WP_166181467.1
Coordinates 607989..608564 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag G7090_RS02905 Protein ID WP_106995644.1
Coordinates 608564..609025 (-) Length 154 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G7090_RS02895 607101..607700 - 600 WP_106995642.1 response regulator transcription factor -
G7090_RS02900 607989..608564 - 576 WP_166181467.1 PIN domain-containing protein Toxin
G7090_RS02905 608564..609025 - 462 WP_106995644.1 helix-turn-helix domain-containing protein Antitoxin
G7090_RS02910 609181..609567 - 387 WP_106995645.1 VOC family protein -
G7090_RS02915 609569..610726 - 1158 WP_166181468.1 MFS transporter -
G7090_RS02920 610723..610881 - 159 WP_166181469.1 hypothetical protein -
G7090_RS02925 610980..611750 + 771 WP_166181470.1 DeoR/GlpR family DNA-binding transcription regulator -
G7090_RS02930 611747..612043 - 297 WP_166181471.1 SH3 domain-containing protein -
G7090_RS02935 612250..613371 + 1122 WP_166181472.1 cupin domain-containing protein -
G7090_RS02940 613413..613598 - 186 WP_166181473.1 DUF2767 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-114)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21818.05 Da        Isoelectric Point: 4.8643

>T151571 WP_166181467.1 NZ_CP049786:c608564-607989 [Leclercia sp. 29361]
MTHSPYPVVLDACVLYPSMLRDLLMHIGKTGLYQPKWTTQIHDEWQRNLLINRPDITPDQLKRTEMLMNKTFGDACVSGY
ESIIDGLNLPDQDDRHVLAAAIRSDSEVIVTYNLVDFPGGNLAEFDVEALHPDEFLSDLFDLNHALVLEAVRMQRSHLRH
PPLTPDQFLQGLLQLGLPKTVTELEKYRVMI

Download         Length: 576 bp

>T151571 NZ_CP065612:c35432-35157 [Escherichia coli]
ATGGAACTGAAGTGGACCAGTAAGGCACTTTCTGATTTGGCGCGGTTATATGATTTTCTGGTGCTGGCCAGTAAACCTGC
TGCCGCCAGAACGGTGCAGTCCCTGACACAGGCGCCGGTCATTCTGTTAACTCATCCACGTATGGGAGAACAGTTGTTTC
AGTTTGAACCCAGGGAGGTCAGACGGATTTTTACTGGCGAGTACGAAATCCGTTACGAACTTACTGGCCAGACTATTTAT
GTATTGCGCCTGTGGCACACACGAGAGAACAGGTAG

Antitoxin


Download         Length: 154 a.a.        Molecular weight: 17085.59 Da        Isoelectric Point: 6.3368

>AT151571 WP_106995644.1 NZ_CP049786:c609025-608564 [Leclercia sp. 29361]
MTNSLLNSLTLPAPKEIEAAVRGQRELATFLSTKQETQKITIQDAQDVTHQIELPTSSLTLLMSILGELAAGNAVQVVPV
HAELTTQEAANILNVSRPHMVKLLEEGKLPFHKTGRHRRILFADLMKYKDQRDAESIQALRELAEQSQELGFY

Download         Length: 462 bp

>AT151571 NZ_CP065612:c35716-35432 [Escherichia coli]
ATGCAAATGAAAAACAATACCGCACAAGCAACAAAAGTAATTACCGCGCATGTGCCATTACCTATGGCTGATAAAGTCGA
CCAGATGGCCGCCAGACTGGAACGCTCCCGGGGCTGGGTTATCAAACAGGCGCTTTCTGCATGGCTTGCCCAAGAGGAGG
AGTGTAATCGCCTGACGCTGGAAGCCCTGGACGATGTGACATCCGGACAGGTTATCGACCATCAGGCTGTACAGGCCTGG
GCGGACAGCCTCAGTACTGACCATCCGTTACCGGTGCCACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References