Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | omega-epsilon-zeta/zeta-epsilon |
| Location | 1249885..1251022 | Replicon | chromosome |
| Accession | NZ_CP049740 | ||
| Organism | Jeotgalibaca arthritidis strain CECT 9157 | ||
Toxin (Protein)
| Gene name | zeta | Uniprot ID | - |
| Locus tag | G7057_RS06460 | Protein ID | WP_166162141.1 |
| Coordinates | 1250159..1251022 (+) | Length | 288 a.a. |
Antitoxin (Protein)
| Gene name | epsilon | Uniprot ID | Q9AL19 |
| Locus tag | G7057_RS06455 | Protein ID | WP_002326825.1 |
| Coordinates | 1249885..1250157 (+) | Length | 91 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| G7057_RS06430 | 1245300..1246784 | + | 1485 | WP_002294513.1 | ABC-F type ribosomal protection protein Lsa(E) | - |
| G7057_RS06435 | 1246838..1247641 | + | 804 | WP_002294514.1 | lincosamide nucleotidyltransferase Lnu(B) | - |
| G7057_RS06440 | 1248301..1248561 | + | 261 | WP_166164110.1 | topoisomerase DNA-binding C4 zinc finger domain-containing protein | - |
| G7057_RS06445 | 1248664..1249560 | + | 897 | WP_193566075.1 | ParA family protein | - |
| G7057_RS06450 | 1249658..1249867 | + | 210 | WP_000527318.1 | peptide-binding protein | - |
| G7057_RS06455 | 1249885..1250157 | + | 273 | WP_002326825.1 | antitoxin | Antitoxin |
| G7057_RS06460 | 1250159..1251022 | + | 864 | WP_166162141.1 | zeta toxin family protein | Toxin |
| G7057_RS06465 | 1251132..1251425 | + | 294 | Protein_1221 | GNAT family N-acetyltransferase | - |
| G7057_RS06470 | 1252082..1252288 | + | 207 | WP_166162143.1 | helix-turn-helix transcriptional regulator | - |
| G7057_RS06475 | 1252290..1252730 | + | 441 | WP_166162144.1 | DUF2207 domain-containing protein | - |
| G7057_RS06480 | 1252976..1253317 | + | 342 | WP_166162145.1 | TetR/AcrR family transcriptional regulator; helix-turn-helix transcriptional regulator | - |
| G7057_RS06485 | 1253323..1253694 | + | 372 | WP_166162146.1 | hypothetical protein | - |
| G7057_RS06490 | 1253862..1254632 | + | 771 | WP_166162147.1 | CPBP family intramembrane metalloprotease | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 288 a.a. Molecular weight: 32672.47 Da Isoelectric Point: 9.2301
>T151512 WP_166162141.1 NZ_CP049740:1250159-1251022 [Jeotgalibaca arthritidis]
MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGSGKTSLRSAISEETQGNVVIIDNDTFKQQHPNFDELV
KLYEKDVVKYVTPYSNRMTEAIISRLRDKGYNLVIEGTGRTTDVPIQTATMLQAKDYETKMYVMAVPKINSYLGTIERYE
TMYADEPMTARATPKQAHDIVVKNLPNNLELLKKTGLFSDIRLYNREGVKLYSSLETPSISPKETLEKELNRKVSSKEIQ
PTLERIEQKMVLNKHQEAPEFKAIQQKLESLRPPTPPIPKTPKLPGL
MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGSGKTSLRSAISEETQGNVVIIDNDTFKQQHPNFDELV
KLYEKDVVKYVTPYSNRMTEAIISRLRDKGYNLVIEGTGRTTDVPIQTATMLQAKDYETKMYVMAVPKINSYLGTIERYE
TMYADEPMTARATPKQAHDIVVKNLPNNLELLKKTGLFSDIRLYNREGVKLYSSLETPSISPKETLEKELNRKVSSKEIQ
PTLERIEQKMVLNKHQEAPEFKAIQQKLESLRPPTPPIPKTPKLPGL
Download Length: 864 bp
>T151512 NZ_CP065600:2297345-2297842 [Burkholderia glumae]
GTGACGGGCTGGCGCGCGCCCGAACCGCTCAGCGACGCGCACGGGCTCGACGATTTCGATTCCGGCGTCGCGAGCCTCGA
CACGTGGCTCAAACGCCGTGCACTGGCCAATCAGCGTAGCGGTGCGTCGCGGACCTTTGTGGCGACGCGAGACGGTCGAG
TGGGGGCGTACTACGCACTCGCGTCCGGCGCGGTTACGCTCGAGGTCGCACCGGGCCGCTTCCGGCGCAACATGCCCGAT
CCGATACCGGTGGTTGTGCTCGGGCGTCTCGCCGTCGATCGCGCCCATCAGGGCATTGGGGTTGGGCGTGCGCTGGTACG
CGATGCCGGCTTGCGTGTGTTGCACGCCGCAGCGGCCATCGGGATTCGCGGCCTGATCGTGCATGCACTCTCGGACTCGG
CCAAGGCGTTCTATGAGCGGGTCGGCTTTGAGGCGTCGCCGCTCGATCCGATGCTGCTCCTGATCACGCTGGCCGACCTC
GAGCACGCCTTGTCATGA
GTGACGGGCTGGCGCGCGCCCGAACCGCTCAGCGACGCGCACGGGCTCGACGATTTCGATTCCGGCGTCGCGAGCCTCGA
CACGTGGCTCAAACGCCGTGCACTGGCCAATCAGCGTAGCGGTGCGTCGCGGACCTTTGTGGCGACGCGAGACGGTCGAG
TGGGGGCGTACTACGCACTCGCGTCCGGCGCGGTTACGCTCGAGGTCGCACCGGGCCGCTTCCGGCGCAACATGCCCGAT
CCGATACCGGTGGTTGTGCTCGGGCGTCTCGCCGTCGATCGCGCCCATCAGGGCATTGGGGTTGGGCGTGCGCTGGTACG
CGATGCCGGCTTGCGTGTGTTGCACGCCGCAGCGGCCATCGGGATTCGCGGCCTGATCGTGCATGCACTCTCGGACTCGG
CCAAGGCGTTCTATGAGCGGGTCGGCTTTGAGGCGTCGCCGCTCGATCCGATGCTGCTCCTGATCACGCTGGCCGACCTC
GAGCACGCCTTGTCATGA
Antitoxin
Download Length: 91 a.a. Molecular weight: 10720.17 Da Isoelectric Point: 4.4865
>AT151512 WP_002326825.1 NZ_CP049740:1249885-1250157 [Jeotgalibaca arthritidis]
MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEVNLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYS
KQILTKEKVA
MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEVNLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYS
KQILTKEKVA
Download Length: 273 bp
>AT151512 NZ_CP065600:2297067-2297348 [Burkholderia glumae]
ATGACCTCGACCACCCCACGCGACACTCTGAACCTACGCATTCGTCCTGACGATCGCAGCTTGATTGACCGCGCCGCAGC
GGCCGCCCACAAAACGCGTACCGACTTCGTTCTGGACGCAGCGCGGGCCGCCGCCGAACAGACCTTGCTCGACCAGGTTG
TTCTGAGCGCCGAGCCGCAGGCCTACGCGGCCTTCCTGGCGCGTTTGGACGAGCCCGTCCAACCGAACGAGGCATTGCGC
CAGACCATGCAGACACGCGCGCCCTGGGACCCCGCTGCGTGA
ATGACCTCGACCACCCCACGCGACACTCTGAACCTACGCATTCGTCCTGACGATCGCAGCTTGATTGACCGCGCCGCAGC
GGCCGCCCACAAAACGCGTACCGACTTCGTTCTGGACGCAGCGCGGGCCGCCGCCGAACAGACCTTGCTCGACCAGGTTG
TTCTGAGCGCCGAGCCGCAGGCCTACGCGGCCTTCCTGGCGCGTTTGGACGAGCCCGTCCAACCGAACGAGGCATTGCGC
CAGACCATGCAGACACGCGCGCCCTGGGACCCCGCTGCGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|