Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
Location | 5380153..5381879 | Replicon | chromosome |
Accession | NZ_CP049737 | ||
Organism | Pseudomonas sp. AN-B15 |
Toxin (Protein)
Gene name | pmenT | Uniprot ID | - |
Locus tag | GTQ41_RS24355 | Protein ID | WP_047296844.1 |
Coordinates | 5380153..5380797 (+) | Length | 215 a.a. |
Antitoxin (Protein)
Gene name | pmenA | Uniprot ID | - |
Locus tag | GTQ41_RS24360 | Protein ID | WP_047296845.1 |
Coordinates | 5380794..5381879 (+) | Length | 362 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GTQ41_RS24335 (GTQ41_24370) | 5375460..5376638 | - | 1179 | WP_080963312.1 | restriction endonuclease subunit S | - |
GTQ41_RS24340 (GTQ41_24375) | 5376644..5378182 | - | 1539 | WP_217325370.1 | class I SAM-dependent DNA methyltransferase | - |
GTQ41_RS24345 (GTQ41_24380) | 5378469..5379389 | + | 921 | WP_047296842.1 | restriction endonuclease | - |
GTQ41_RS24350 (GTQ41_24385) | 5379575..5380156 | + | 582 | WP_047296843.1 | DarT ssDNA thymidine ADP-ribosyltransferase family protein | - |
GTQ41_RS24355 (GTQ41_24390) | 5380153..5380797 | + | 645 | WP_047296844.1 | DUF4433 domain-containing protein | Toxin |
GTQ41_RS24360 (GTQ41_24395) | 5380794..5381879 | + | 1086 | WP_047296845.1 | macro domain-containing protein | Antitoxin |
GTQ41_RS24365 (GTQ41_24400) | 5382053..5382613 | + | 561 | WP_047296847.1 | hypothetical protein | - |
GTQ41_RS24370 (GTQ41_24405) | 5382629..5383063 | + | 435 | WP_047296849.1 | hypothetical protein | - |
GTQ41_RS24375 (GTQ41_24410) | 5383087..5383899 | - | 813 | WP_047296851.1 | DUF2135 domain-containing protein | - |
GTQ41_RS24380 (GTQ41_24415) | 5383903..5385522 | - | 1620 | WP_047296853.1 | DUF2300 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 5370395..5381879 | 11484 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 215 a.a. Molecular weight: 24870.42 Da Isoelectric Point: 6.5828
>T151480 WP_047296844.1 NZ_CP049737:5380153-5380797 [Pseudomonas sp. AN-B15]
MIYTNLNPEKALIWRIVHRDNLPWILDNGLHCANSEVQAPQYVNIGNVELIDKRRTRQVPIAPEGVLADYVPFYFTPFSV
MMQNIHSGWSVQQRSNDEIVILVSSLYRVEELGLPFVFTNAHAYPSWTNYYSDLANLDQVDWSILQRRDFKRDPDDPRKM
ERYQAEALIHHHLPITGLLGIMCHTDAMKVRIEADVAARGLTLPVHARPTWYFQ
MIYTNLNPEKALIWRIVHRDNLPWILDNGLHCANSEVQAPQYVNIGNVELIDKRRTRQVPIAPEGVLADYVPFYFTPFSV
MMQNIHSGWSVQQRSNDEIVILVSSLYRVEELGLPFVFTNAHAYPSWTNYYSDLANLDQVDWSILQRRDFKRDPDDPRKM
ERYQAEALIHHHLPITGLLGIMCHTDAMKVRIEADVAARGLTLPVHARPTWYFQ
Download Length: 645 bp
>T151480 NZ_CP049737:5380153-5380797 [Pseudomonas sp. AN-B15]
ATGATCTATACCAACCTGAATCCAGAGAAAGCTCTGATTTGGCGTATCGTCCATCGCGATAACCTGCCCTGGATTCTGGA
CAACGGTCTGCATTGTGCAAACTCGGAAGTACAGGCACCTCAGTACGTGAATATCGGCAACGTCGAATTGATCGACAAGC
GCCGTACCCGTCAGGTGCCTATTGCGCCCGAAGGCGTTCTGGCCGACTACGTGCCCTTCTATTTCACACCTTTCTCGGTG
ATGATGCAGAACATTCACTCTGGGTGGAGTGTTCAGCAACGCAGCAACGACGAGATCGTGATTCTGGTCTCGAGCCTTTA
TCGCGTTGAAGAGCTTGGCCTACCGTTTGTCTTCACAAACGCACATGCTTACCCGAGTTGGACAAACTACTACAGCGATC
TGGCGAATCTCGACCAGGTCGATTGGTCTATCCTTCAACGGCGCGACTTCAAGCGCGATCCTGACGACCCTCGCAAAATG
GAGCGTTATCAGGCTGAGGCGCTGATCCACCATCATTTACCGATTACGGGACTACTGGGCATCATGTGCCACACCGATGC
AATGAAAGTACGCATAGAAGCAGACGTTGCCGCCAGAGGCCTGACGTTGCCGGTTCATGCGCGCCCCACATGGTATTTCC
AATGA
ATGATCTATACCAACCTGAATCCAGAGAAAGCTCTGATTTGGCGTATCGTCCATCGCGATAACCTGCCCTGGATTCTGGA
CAACGGTCTGCATTGTGCAAACTCGGAAGTACAGGCACCTCAGTACGTGAATATCGGCAACGTCGAATTGATCGACAAGC
GCCGTACCCGTCAGGTGCCTATTGCGCCCGAAGGCGTTCTGGCCGACTACGTGCCCTTCTATTTCACACCTTTCTCGGTG
ATGATGCAGAACATTCACTCTGGGTGGAGTGTTCAGCAACGCAGCAACGACGAGATCGTGATTCTGGTCTCGAGCCTTTA
TCGCGTTGAAGAGCTTGGCCTACCGTTTGTCTTCACAAACGCACATGCTTACCCGAGTTGGACAAACTACTACAGCGATC
TGGCGAATCTCGACCAGGTCGATTGGTCTATCCTTCAACGGCGCGACTTCAAGCGCGATCCTGACGACCCTCGCAAAATG
GAGCGTTATCAGGCTGAGGCGCTGATCCACCATCATTTACCGATTACGGGACTACTGGGCATCATGTGCCACACCGATGC
AATGAAAGTACGCATAGAAGCAGACGTTGCCGCCAGAGGCCTGACGTTGCCGGTTCATGCGCGCCCCACATGGTATTTCC
AATGA
Antitoxin
Download Length: 362 a.a. Molecular weight: 40658.77 Da Isoelectric Point: 6.5088
>AT151480 WP_047296845.1 NZ_CP049737:5380794-5381879 [Pseudomonas sp. AN-B15]
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFAQNYRVYAAACKAGEVETGKMHVTATNELDGPRWIVNFPTK
RHWRSPSQMAWITEGLHDLRRFLLENDVKSVAVPPLGAGNGGLKWPEVREQIVEVLGDLDVDILVFEPSNQYLNVAKRDG
VEQLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKTPDTENPLNLKFVAHKFGPYANRLEHLLNNLDGSYLH
CDKRISDAGITDVIWFDQDRKTFLQTYLKTEAKEYSQALERTAELIDGFESPFGMELLATVDWLLIRERIAPTIPAVRKA
MKNWDGGAAAAVRKNKLFDDQALGIAIARLTSTSFSPEIAA
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFAQNYRVYAAACKAGEVETGKMHVTATNELDGPRWIVNFPTK
RHWRSPSQMAWITEGLHDLRRFLLENDVKSVAVPPLGAGNGGLKWPEVREQIVEVLGDLDVDILVFEPSNQYLNVAKRDG
VEQLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKTPDTENPLNLKFVAHKFGPYANRLEHLLNNLDGSYLH
CDKRISDAGITDVIWFDQDRKTFLQTYLKTEAKEYSQALERTAELIDGFESPFGMELLATVDWLLIRERIAPTIPAVRKA
MKNWDGGAAAAVRKNKLFDDQALGIAIARLTSTSFSPEIAA
Download Length: 1086 bp
>AT151480 NZ_CP049737:5380794-5381879 [Pseudomonas sp. AN-B15]
ATGATCAGATTCACCCAAGGCAACCTGCTGGAAGCCAAAACCGAAGCCCTCGTCAACACGGTGAACACCGTTGGCGTGAT
GGGTAAGGGCATCGCGCTGATGTTCAAAGAGCGCTTTGCGCAGAATTACCGCGTGTATGCAGCGGCATGTAAGGCCGGGG
AAGTAGAAACCGGCAAGATGCATGTGACGGCCACCAACGAACTCGATGGCCCCCGCTGGATCGTGAATTTCCCGACCAAG
CGCCATTGGCGTTCTCCGTCGCAAATGGCGTGGATAACCGAAGGTTTGCATGACCTGCGACGGTTCCTGCTTGAAAACGA
TGTGAAGTCCGTTGCTGTTCCTCCGCTGGGCGCTGGTAACGGTGGTTTGAAGTGGCCCGAAGTGCGCGAGCAGATTGTAG
AAGTGCTGGGTGACCTGGATGTCGATATATTAGTGTTCGAACCCTCCAATCAGTATCTGAATGTCGCTAAGCGCGATGGC
GTTGAGCAGCTCACTCCGGCACGCGCACTGATTGCTGAACTGGTTCGGCGTTATTGGGTTCTGGGCATGGAATGCAGCCT
GCTTGAAATTCAGAAACTGGCTTGGTTTCTTGAGCGTGCAATCGAGAAAACTCCAGATACCGAGAATCCGCTAAACCTCA
AATTTGTCGCTCATAAATTCGGTCCGTATGCCAATCGATTGGAGCATCTGCTCAACAATCTGGATGGCAGCTATCTACAT
TGCGACAAGCGCATCAGTGATGCTGGAATCACCGATGTCATTTGGTTTGATCAAGATCGCAAAACGTTTTTGCAGACCTA
CCTCAAGACCGAAGCCAAGGAATACTCCCAGGCTTTAGAGCGAACGGCCGAATTGATCGATGGTTTTGAGTCACCTTTCG
GCATGGAGTTGCTGGCGACCGTTGATTGGTTGCTGATTCGGGAAAGGATTGCTCCAACCATTCCTGCGGTACGTAAAGCA
ATGAAGAATTGGGACGGCGGAGCCGCAGCTGCGGTGCGTAAAAACAAGTTATTCGATGATCAGGCACTAGGCATTGCGAT
CGCTCGTCTGACATCCACCAGCTTCAGCCCGGAAATAGCGGCCTGA
ATGATCAGATTCACCCAAGGCAACCTGCTGGAAGCCAAAACCGAAGCCCTCGTCAACACGGTGAACACCGTTGGCGTGAT
GGGTAAGGGCATCGCGCTGATGTTCAAAGAGCGCTTTGCGCAGAATTACCGCGTGTATGCAGCGGCATGTAAGGCCGGGG
AAGTAGAAACCGGCAAGATGCATGTGACGGCCACCAACGAACTCGATGGCCCCCGCTGGATCGTGAATTTCCCGACCAAG
CGCCATTGGCGTTCTCCGTCGCAAATGGCGTGGATAACCGAAGGTTTGCATGACCTGCGACGGTTCCTGCTTGAAAACGA
TGTGAAGTCCGTTGCTGTTCCTCCGCTGGGCGCTGGTAACGGTGGTTTGAAGTGGCCCGAAGTGCGCGAGCAGATTGTAG
AAGTGCTGGGTGACCTGGATGTCGATATATTAGTGTTCGAACCCTCCAATCAGTATCTGAATGTCGCTAAGCGCGATGGC
GTTGAGCAGCTCACTCCGGCACGCGCACTGATTGCTGAACTGGTTCGGCGTTATTGGGTTCTGGGCATGGAATGCAGCCT
GCTTGAAATTCAGAAACTGGCTTGGTTTCTTGAGCGTGCAATCGAGAAAACTCCAGATACCGAGAATCCGCTAAACCTCA
AATTTGTCGCTCATAAATTCGGTCCGTATGCCAATCGATTGGAGCATCTGCTCAACAATCTGGATGGCAGCTATCTACAT
TGCGACAAGCGCATCAGTGATGCTGGAATCACCGATGTCATTTGGTTTGATCAAGATCGCAAAACGTTTTTGCAGACCTA
CCTCAAGACCGAAGCCAAGGAATACTCCCAGGCTTTAGAGCGAACGGCCGAATTGATCGATGGTTTTGAGTCACCTTTCG
GCATGGAGTTGCTGGCGACCGTTGATTGGTTGCTGATTCGGGAAAGGATTGCTCCAACCATTCCTGCGGTACGTAAAGCA
ATGAAGAATTGGGACGGCGGAGCCGCAGCTGCGGTGCGTAAAAACAAGTTATTCGATGATCAGGCACTAGGCATTGCGAT
CGCTCGTCTGACATCCACCAGCTTCAGCCCGGAAATAGCGGCCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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