151480

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 5380153..5381879 Replicon chromosome
Accession NZ_CP049737
Organism Pseudomonas sp. AN-B15

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag GTQ41_RS24355 Protein ID WP_047296844.1
Coordinates 5380153..5380797 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag GTQ41_RS24360 Protein ID WP_047296845.1
Coordinates 5380794..5381879 (+) Length 362 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GTQ41_RS24335 (GTQ41_24370) 5375460..5376638 - 1179 WP_080963312.1 restriction endonuclease subunit S -
GTQ41_RS24340 (GTQ41_24375) 5376644..5378182 - 1539 WP_217325370.1 class I SAM-dependent DNA methyltransferase -
GTQ41_RS24345 (GTQ41_24380) 5378469..5379389 + 921 WP_047296842.1 restriction endonuclease -
GTQ41_RS24350 (GTQ41_24385) 5379575..5380156 + 582 WP_047296843.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
GTQ41_RS24355 (GTQ41_24390) 5380153..5380797 + 645 WP_047296844.1 DUF4433 domain-containing protein Toxin
GTQ41_RS24360 (GTQ41_24395) 5380794..5381879 + 1086 WP_047296845.1 macro domain-containing protein Antitoxin
GTQ41_RS24365 (GTQ41_24400) 5382053..5382613 + 561 WP_047296847.1 hypothetical protein -
GTQ41_RS24370 (GTQ41_24405) 5382629..5383063 + 435 WP_047296849.1 hypothetical protein -
GTQ41_RS24375 (GTQ41_24410) 5383087..5383899 - 813 WP_047296851.1 DUF2135 domain-containing protein -
GTQ41_RS24380 (GTQ41_24415) 5383903..5385522 - 1620 WP_047296853.1 DUF2300 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 5370395..5381879 11484


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(14-213)

Antitoxin

(18-130)


Sequences


Toxin        


Download         Length: 215 a.a.        Molecular weight: 24870.42 Da        Isoelectric Point: 6.5828

>T151480 WP_047296844.1 NZ_CP049737:5380153-5380797 [Pseudomonas sp. AN-B15]
MIYTNLNPEKALIWRIVHRDNLPWILDNGLHCANSEVQAPQYVNIGNVELIDKRRTRQVPIAPEGVLADYVPFYFTPFSV
MMQNIHSGWSVQQRSNDEIVILVSSLYRVEELGLPFVFTNAHAYPSWTNYYSDLANLDQVDWSILQRRDFKRDPDDPRKM
ERYQAEALIHHHLPITGLLGIMCHTDAMKVRIEADVAARGLTLPVHARPTWYFQ

Download         Length: 645 bp

>T151480 NZ_CP049737:5380153-5380797 [Pseudomonas sp. AN-B15]
ATGATCTATACCAACCTGAATCCAGAGAAAGCTCTGATTTGGCGTATCGTCCATCGCGATAACCTGCCCTGGATTCTGGA
CAACGGTCTGCATTGTGCAAACTCGGAAGTACAGGCACCTCAGTACGTGAATATCGGCAACGTCGAATTGATCGACAAGC
GCCGTACCCGTCAGGTGCCTATTGCGCCCGAAGGCGTTCTGGCCGACTACGTGCCCTTCTATTTCACACCTTTCTCGGTG
ATGATGCAGAACATTCACTCTGGGTGGAGTGTTCAGCAACGCAGCAACGACGAGATCGTGATTCTGGTCTCGAGCCTTTA
TCGCGTTGAAGAGCTTGGCCTACCGTTTGTCTTCACAAACGCACATGCTTACCCGAGTTGGACAAACTACTACAGCGATC
TGGCGAATCTCGACCAGGTCGATTGGTCTATCCTTCAACGGCGCGACTTCAAGCGCGATCCTGACGACCCTCGCAAAATG
GAGCGTTATCAGGCTGAGGCGCTGATCCACCATCATTTACCGATTACGGGACTACTGGGCATCATGTGCCACACCGATGC
AATGAAAGTACGCATAGAAGCAGACGTTGCCGCCAGAGGCCTGACGTTGCCGGTTCATGCGCGCCCCACATGGTATTTCC
AATGA

Antitoxin


Download         Length: 362 a.a.        Molecular weight: 40658.77 Da        Isoelectric Point: 6.5088

>AT151480 WP_047296845.1 NZ_CP049737:5380794-5381879 [Pseudomonas sp. AN-B15]
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFAQNYRVYAAACKAGEVETGKMHVTATNELDGPRWIVNFPTK
RHWRSPSQMAWITEGLHDLRRFLLENDVKSVAVPPLGAGNGGLKWPEVREQIVEVLGDLDVDILVFEPSNQYLNVAKRDG
VEQLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKTPDTENPLNLKFVAHKFGPYANRLEHLLNNLDGSYLH
CDKRISDAGITDVIWFDQDRKTFLQTYLKTEAKEYSQALERTAELIDGFESPFGMELLATVDWLLIRERIAPTIPAVRKA
MKNWDGGAAAAVRKNKLFDDQALGIAIARLTSTSFSPEIAA

Download         Length: 1086 bp

>AT151480 NZ_CP049737:5380794-5381879 [Pseudomonas sp. AN-B15]
ATGATCAGATTCACCCAAGGCAACCTGCTGGAAGCCAAAACCGAAGCCCTCGTCAACACGGTGAACACCGTTGGCGTGAT
GGGTAAGGGCATCGCGCTGATGTTCAAAGAGCGCTTTGCGCAGAATTACCGCGTGTATGCAGCGGCATGTAAGGCCGGGG
AAGTAGAAACCGGCAAGATGCATGTGACGGCCACCAACGAACTCGATGGCCCCCGCTGGATCGTGAATTTCCCGACCAAG
CGCCATTGGCGTTCTCCGTCGCAAATGGCGTGGATAACCGAAGGTTTGCATGACCTGCGACGGTTCCTGCTTGAAAACGA
TGTGAAGTCCGTTGCTGTTCCTCCGCTGGGCGCTGGTAACGGTGGTTTGAAGTGGCCCGAAGTGCGCGAGCAGATTGTAG
AAGTGCTGGGTGACCTGGATGTCGATATATTAGTGTTCGAACCCTCCAATCAGTATCTGAATGTCGCTAAGCGCGATGGC
GTTGAGCAGCTCACTCCGGCACGCGCACTGATTGCTGAACTGGTTCGGCGTTATTGGGTTCTGGGCATGGAATGCAGCCT
GCTTGAAATTCAGAAACTGGCTTGGTTTCTTGAGCGTGCAATCGAGAAAACTCCAGATACCGAGAATCCGCTAAACCTCA
AATTTGTCGCTCATAAATTCGGTCCGTATGCCAATCGATTGGAGCATCTGCTCAACAATCTGGATGGCAGCTATCTACAT
TGCGACAAGCGCATCAGTGATGCTGGAATCACCGATGTCATTTGGTTTGATCAAGATCGCAAAACGTTTTTGCAGACCTA
CCTCAAGACCGAAGCCAAGGAATACTCCCAGGCTTTAGAGCGAACGGCCGAATTGATCGATGGTTTTGAGTCACCTTTCG
GCATGGAGTTGCTGGCGACCGTTGATTGGTTGCTGATTCGGGAAAGGATTGCTCCAACCATTCCTGCGGTACGTAAAGCA
ATGAAGAATTGGGACGGCGGAGCCGCAGCTGCGGTGCGTAAAAACAAGTTATTCGATGATCAGGCACTAGGCATTGCGAT
CGCTCGTCTGACATCCACCAGCTTCAGCCCGGAAATAGCGGCCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References