Detailed information of TA system TA151479

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/COG5606-COG4679
• Location: 4442362..4442980
• Replicon: chromosome
• Accession: NZ_CP049737
• Organism: Pseudomonas sp. AN-B15

Toxin (Protein)

• Gene name: tad
• Uniprot ID: -
• Locus tag: GTQ41_RS20115
• Protein ID: WP_179294964.1
• Coordinates: 4442362..4442673 (+)
• Length: 104 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: -
• Locus tag: GTQ41_RS20120
• Protein ID: WP_047295878.1
• Coordinates: 4442660..4442980 (+)
• Length: 107 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GTQ41_RS20085 (GTQ41_20105)	4438395..4438628	+	234	WP_047295864.1	hypothetical protein	-
GTQ41_RS20090 (GTQ41_20110)	4438671..4438901	+	231	WP_047295866.1	hypothetical protein	-
GTQ41_RS20095 (GTQ41_20115)	4439171..4440154	+	984	WP_047295868.1	hypothetical protein	-
GTQ41_RS20100 (GTQ41_20120)	4440159..4440974	-	816	WP_047295871.1	sulfite exporter TauE/SafE family protein	-
GTQ41_RS20105 (GTQ41_20125)	4441087..4441854	+	768	WP_047295872.1	helix-turn-helix transcriptional regulator	-
GTQ41_RS20110 (GTQ41_20130)	4441948..4442262	+	315	WP_047295874.1	hypothetical protein	-
GTQ41_RS20115 (GTQ41_20135)	4442362..4442673	+	312	WP_179294964.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
GTQ41_RS20120 (GTQ41_20140)	4442660..4442980	+	321	WP_047295878.1	helix-turn-helix transcriptional regulator	Antitoxin
GTQ41_RS20125 (GTQ41_20145)	4442992..4444047	-	1056	WP_047295881.1	MBL fold metallo-hydrolase	-
GTQ41_RS20130 (GTQ41_20150)	4444264..4444872	+	609	WP_047295884.1	TetR/AcrR family transcriptional regulator	-
GTQ41_RS20135 (GTQ41_20155)	4445103..4446422	+	1320	WP_047295886.1	PAS domain-containing methyl-accepting chemotaxis protein	-
GTQ41_RS20140 (GTQ41_20160)	4446595..4447128	+	534	WP_041066470.1	DUF1003 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (1-88)

Antitoxin

• Cro/C1-type helix-turn-helix domain (30-85)

Sequences

Toxin

Protein

• Length: 104 a.a.
• Molecular weight: 11400.86 Da
• Isoelectric Point: 8.0425

>T151479 WP_179294964.1 NZ_CP049737:4442362-4442673 [Pseudomonas sp. AN-B15]
MPTDVQDVFGYALDLAQSGLKHPDAKPLKGFGGAGVLELIEDFDTNTYRAIYTVRFGSAIYVLHCFQKKSKTGIKTAQSD
IDLIRNRLRAAQDHAKGSENDRN

Nucleotide

• Length: 312 bp

>T151479 NZ_CP065534:3425307-3425786 [Lonsdalea populi]
GTGGGAATAACGGCACCTGAATTATTGCTGCCTCAACATGCAGTTGTGGATTTTCATTGTTCCGAGCCGTCATTGAATGA
ATGGCTGAAACGCAAGGCGTTAAAAAATCAGACGCTGGGCGCTTCACGCACCTTCGTGGTGTGTGAAGCCGGTACACAGC
GTGTGGTGGGGTTCTATGCCCTCGCGTCGGGTAGCATCCAGCGTCAGGTTGCACCGGGCGCATTCCGGCGCAATATGCCT
GACCCCATTCCTGTTCTGGTACTTGGCCGATTAGCCGTTGATGAACGTTATCAACGCATGGGGATCGGTGCCGGGCTTCT
GAAAGATGCGGTACTCCGCTCCCGCAATGTAGCGCAGCAGGTAGGCAACAAAGCGTTATTGGTACATGCGTTATCTGATG
AGGCAAAAGCGTTCTACCAATACTGGGGTTTTGTCGCGTCAGAAATACAGGAACACACCTTATTATTATCGTTATGGTAA

Antitoxin

Protein

• Length: 107 a.a.
• Molecular weight: 11777.72 Da
• Isoelectric Point: 8.0411

>AT151479 WP_047295878.1 NZ_CP049737:4442660-4442980 [Pseudomonas sp. AN-B15]
MIEIEEGSGNVYQDLELPNASEMQVKSQLAAKIGEIIKARHLTQIQASEILGLSQPKLSEMLRGKFRGISEAKMMECLSH
LGRDVQIVVKSAPRSRKEGRIEVVFA

Nucleotide

• Length: 321 bp

>AT151479 NZ_CP065534:3425044-3425316 [Lonsdalea populi]
ATGCGAACAGAGACAAAAGAAATGCCGATTAATATTCGTGCTAAAGCATCACAGCGGGAGCTGATTGATGTCGCCGCTAA
ATTGCTGTCGAAATCAAGAACAGAGTTTATCCTTGATGCTGCCTGCCGTGAGGCTGAGGATGTGTTGTTGGATCAACGGC
TGTTTCTGGTCAATGATGAACAATATGATGCTTTCATTCAGGTGCTGGAATCACCTGTCACAGATAATCCGCGTGTGAAT
GCATTACTGAACAGGAAATCTCCGTGGGAATAA