Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | hicAB/HicA-HicB |
| Location | 307837..308480 | Replicon | chromosome |
| Accession | NZ_CP049737 | ||
| Organism | Pseudomonas sp. AN-B15 | ||
Toxin (Protein)
| Gene name | hicA | Uniprot ID | A0A423N608 |
| Locus tag | GTQ41_RS01360 | Protein ID | WP_027611194.1 |
| Coordinates | 307837..308019 (+) | Length | 61 a.a. |
Antitoxin (Protein)
| Gene name | hicB | Uniprot ID | - |
| Locus tag | GTQ41_RS01365 | Protein ID | WP_047291023.1 |
| Coordinates | 308079..308480 (+) | Length | 134 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GTQ41_RS01345 (GTQ41_01345) | 303843..304769 | + | 927 | WP_041071188.1 | serine acetyltransferase | - |
| GTQ41_RS01350 (GTQ41_01350) | 305194..307155 | + | 1962 | WP_196302412.1 | choline transporter BetT | - |
| GTQ41_RS01355 (GTQ41_01355) | 307180..307440 | - | 261 | WP_025110994.1 | hypothetical protein | - |
| GTQ41_RS01360 (GTQ41_01360) | 307837..308019 | + | 183 | WP_027611194.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
| GTQ41_RS01365 (GTQ41_01365) | 308079..308480 | + | 402 | WP_047291023.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
| GTQ41_RS01370 (GTQ41_01370) | 308574..309611 | - | 1038 | WP_047290803.1 | LacI family DNA-binding transcriptional regulator | - |
| GTQ41_RS01375 (GTQ41_01375) | 309817..312042 | + | 2226 | WP_047290804.1 | TonB-dependent receptor | - |
| GTQ41_RS01380 (GTQ41_01380) | 312044..313363 | + | 1320 | WP_047290805.1 | LLM class flavin-dependent oxidoreductase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 61 a.a. Molecular weight: 6936.10 Da Isoelectric Point: 10.7459
>T151474 WP_027611194.1 NZ_CP049737:307837-308019 [Pseudomonas sp. AN-B15]
MRSREMIRMIEEDGWYLVAVKGSHHQYKHPRKPGRVTIKHPDSDLPKGTINSILKQAGLK
MRSREMIRMIEEDGWYLVAVKGSHHQYKHPRKPGRVTIKHPDSDLPKGTINSILKQAGLK
Download Length: 183 bp
>T151474 NZ_CP065534:c914309-913653 [Lonsdalea populi]
ATGGCTAATAACTACAGTGCCAGTCTCAACCCACAAAAAGCCCTGATCTGGCGTATTGTCCATCGGGATAATATCCCGTG
GATACTGGACAACGGTCTACACTGCGGCAACAGCCCGGTGCAGGCGGGAAACTGGATCAATATCGGCAACCCGGAGCTTA
TCAGCAAACGCGCCGGGCATCCGGTGCCTGTCGGAACGGGCGGCGTACTGCATGACTATGTGCCGTTTTACTTTACCCCC
TTCTCGCCGATGCTGATGAATATCCACAGCGGGCGTGGCGGCATTAAGCAGCGCCCCAATGAGGAAATCGTCATTCTGGT
CAGCAGCCTGCGCACCGTGGCGGCGCAAAATGTGCCTTTTGTGTTTACCGATAGCCACGCCTACTATAACTGGGCCAACT
ACTACACAGAGTTGGACAACCTGAACCAAATTGACTGGCCTATTTTACAGGCGCGGGATTTCCGCCGCGATCCTGACGAT
CCGGGCAAATTTGAACGCTATCAGGCCGAAGCGCTGATTTGGCAACACTGCCCAATCATACTGCTGGGCGGGATGGTTTG
TTACAACGACAGCGTCAAGTTACAATTAGAACAGTGGCTGTCGCAACGCAATCTGACAATGCCCGTTCACGCACGGGCCG
GGTGGTACTTCTCATGA
ATGGCTAATAACTACAGTGCCAGTCTCAACCCACAAAAAGCCCTGATCTGGCGTATTGTCCATCGGGATAATATCCCGTG
GATACTGGACAACGGTCTACACTGCGGCAACAGCCCGGTGCAGGCGGGAAACTGGATCAATATCGGCAACCCGGAGCTTA
TCAGCAAACGCGCCGGGCATCCGGTGCCTGTCGGAACGGGCGGCGTACTGCATGACTATGTGCCGTTTTACTTTACCCCC
TTCTCGCCGATGCTGATGAATATCCACAGCGGGCGTGGCGGCATTAAGCAGCGCCCCAATGAGGAAATCGTCATTCTGGT
CAGCAGCCTGCGCACCGTGGCGGCGCAAAATGTGCCTTTTGTGTTTACCGATAGCCACGCCTACTATAACTGGGCCAACT
ACTACACAGAGTTGGACAACCTGAACCAAATTGACTGGCCTATTTTACAGGCGCGGGATTTCCGCCGCGATCCTGACGAT
CCGGGCAAATTTGAACGCTATCAGGCCGAAGCGCTGATTTGGCAACACTGCCCAATCATACTGCTGGGCGGGATGGTTTG
TTACAACGACAGCGTCAAGTTACAATTAGAACAGTGGCTGTCGCAACGCAATCTGACAATGCCCGTTCACGCACGGGCCG
GGTGGTACTTCTCATGA
Antitoxin
Download Length: 134 a.a. Molecular weight: 14541.27 Da Isoelectric Point: 4.4631
>AT151474 WP_047291023.1 NZ_CP049737:308079-308480 [Pseudomonas sp. AN-B15]
MKFPVVLHKDADSDYGVIVPDVPGCFSAGSTVAEAFENTQEALALHYEGLVADGAPLPRVRDIDAHLDNPDYAGGIWGVV
DFDITPYFGKSVRFNATLPEQLLERIDQTVRRDQRYSSRSGFLAAAALRELSA
MKFPVVLHKDADSDYGVIVPDVPGCFSAGSTVAEAFENTQEALALHYEGLVADGAPLPRVRDIDAHLDNPDYAGGIWGVV
DFDITPYFGKSVRFNATLPEQLLERIDQTVRRDQRYSSRSGFLAAAALRELSA
Download Length: 402 bp
>AT151474 NZ_CP065534:c913656-912589 [Lonsdalea populi]
ATGATCACATTTACACAAGGCAACTTACTGGATGCGCCCGTGGAAGCACTGGTGAATACGGTTAATACCGTCGGTGTCAT
GGGTAAAGGCATCGCGCTGATGTTCAAAGAGCGCTTTCCCGCCAATATGAAAGCCTACGCTCTCGCCTGCAAACAAAAAC
AGGTGATAACCGGTAAAATGTTTATTACCGAAACTGGCGAACTGATGGGACCGCGCTGGATTGTCAACTTCCCTACCAAA
CAGCACTGGCGCACCGACTCGCGTATGGAGTGGATTGAAGACGGTTTGCAGGACTTACGCCGCTTTTTGATCGAAAAACA
GGTGCAGTCCATCGCCATACCACCGCTGGGGGCAGGCAACGGCGGTCTGAACTGGCCGGACGTTCGAGCGCATATTGAAT
CTGCGCTGGGCGACCTTCAGGACGTTGAAATCCTGATTTATGAGCCCACCGAAAAATACCAGAACGTTGCCAAAAGCACC
GGTGTAAAAAAGCTCACCCCCGCCAGAGCGATGATCGCTGAACTGGTGCGCCGTTACTGGGTGCTGGGGATGGAGTGCAG
CCTGCTGGAGATTCAGAAGCTGGCATGGCTTCTACAGCGTGCCATTAAGTTGCATCAGCAAGAAAACGTGCTGAAACTGC
GATTTGAAGCGCACAACTATGGCCCTTATGCGCACAACCTGACTCATCTGCTTAATGCGCTAGACGGCAACTATCTGAAA
GCGGAAAAACGCATCCCGGACAGCCAGCCGCTGGATGTGATCTGGTTTAACGATCGGGAAAAAGACCACGTAAATACTTA
TCTGAATAGCGAAGCTAAAACGTGGTTGCCAGCATTGGAGCAGGTTAGCCAGTTAATAGACGGCTTTGAATCCCCATTCG
GTATGGAGTTGTTGGCGACCGTGGACTGGTTGCTTACCTGCGACAAATGCCAGCCCACGCTGGACTCCGTTAAAGAGGGG
CTAAGCCAGTGGCCTGCGGGCGAACACTGGGCCAGCCGCAAGATGAAACTATTCGATGATAATAATCTACAATTCGCCAT
TAACCGCGTAATGGAGTTCCATTGCTGA
ATGATCACATTTACACAAGGCAACTTACTGGATGCGCCCGTGGAAGCACTGGTGAATACGGTTAATACCGTCGGTGTCAT
GGGTAAAGGCATCGCGCTGATGTTCAAAGAGCGCTTTCCCGCCAATATGAAAGCCTACGCTCTCGCCTGCAAACAAAAAC
AGGTGATAACCGGTAAAATGTTTATTACCGAAACTGGCGAACTGATGGGACCGCGCTGGATTGTCAACTTCCCTACCAAA
CAGCACTGGCGCACCGACTCGCGTATGGAGTGGATTGAAGACGGTTTGCAGGACTTACGCCGCTTTTTGATCGAAAAACA
GGTGCAGTCCATCGCCATACCACCGCTGGGGGCAGGCAACGGCGGTCTGAACTGGCCGGACGTTCGAGCGCATATTGAAT
CTGCGCTGGGCGACCTTCAGGACGTTGAAATCCTGATTTATGAGCCCACCGAAAAATACCAGAACGTTGCCAAAAGCACC
GGTGTAAAAAAGCTCACCCCCGCCAGAGCGATGATCGCTGAACTGGTGCGCCGTTACTGGGTGCTGGGGATGGAGTGCAG
CCTGCTGGAGATTCAGAAGCTGGCATGGCTTCTACAGCGTGCCATTAAGTTGCATCAGCAAGAAAACGTGCTGAAACTGC
GATTTGAAGCGCACAACTATGGCCCTTATGCGCACAACCTGACTCATCTGCTTAATGCGCTAGACGGCAACTATCTGAAA
GCGGAAAAACGCATCCCGGACAGCCAGCCGCTGGATGTGATCTGGTTTAACGATCGGGAAAAAGACCACGTAAATACTTA
TCTGAATAGCGAAGCTAAAACGTGGTTGCCAGCATTGGAGCAGGTTAGCCAGTTAATAGACGGCTTTGAATCCCCATTCG
GTATGGAGTTGTTGGCGACCGTGGACTGGTTGCTTACCTGCGACAAATGCCAGCCCACGCTGGACTCCGTTAAAGAGGGG
CTAAGCCAGTGGCCTGCGGGCGAACACTGGGCCAGCCGCAAGATGAAACTATTCGATGATAATAATCTACAATTCGCCAT
TAACCGCGTAATGGAGTTCCATTGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|