Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2005780..2005924 Replicon chromosome
Accession NZ_CP049719
Organism Klebsiella pneumoniae strain 06KM907

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2005816..2005918 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2005780..2005924 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G7Z28_RS09825 2000910..2002970 + 2061 WP_004151449.1 oligopeptidase B -
G7Z28_RS09830 2002974..2003633 - 660 WP_002911407.1 exodeoxyribonuclease X -
G7Z28_RS09835 2003712..2003942 - 231 WP_002911406.1 DNA polymerase III subunit theta -
G7Z28_RS09840 2004055..2004429 + 375 WP_004151448.1 CopC domain-containing protein YobA -
G7Z28_RS09845 2004433..2005302 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
G7Z28_RS09850 2005319..2005657 + 339 WP_002911404.1 YebY family protein -
- 2005780..2005924 - 145 - - Antitoxin
- 2005816..2005918 + 103 - - Toxin
G7Z28_RS09855 2006051..2006410 - 360 WP_077253379.1 tyrosine-type recombinase/integrase -
G7Z28_RS09860 2006409..2006888 + 480 WP_032419797.1 lysis protein -
G7Z28_RS09865 2007677..2009182 + 1506 WP_020956680.1 hypothetical protein -
G7Z28_RS09870 2009432..2009860 - 429 WP_032419788.1 type II toxin-antitoxin system PemK/MazF family toxin -
G7Z28_RS09875 2009870..2010151 - 282 WP_032419786.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T151459 NZ_CP049719:2005816-2005918 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT151459 NZ_CP049719:c2005924-2005780 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References