Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2006949..2007093 Replicon chromosome
Accession NZ_CP049716
Organism Klebsiella pneumoniae strain 11KM256

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2006985..2007087 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2006949..2007093 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G7Z27_RS09835 2002079..2004139 + 2061 WP_004151449.1 oligopeptidase B -
G7Z27_RS09840 2004143..2004802 - 660 WP_002911407.1 exodeoxyribonuclease X -
G7Z27_RS09845 2004881..2005111 - 231 WP_002911406.1 DNA polymerase III subunit theta -
G7Z27_RS09850 2005224..2005598 + 375 WP_004151448.1 CopC domain-containing protein YobA -
G7Z27_RS09855 2005602..2006471 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
G7Z27_RS09860 2006488..2006826 + 339 WP_002911404.1 YebY family protein -
- 2006949..2007093 - 145 - - Antitoxin
- 2006985..2007087 + 103 - - Toxin
G7Z27_RS09865 2007220..2007579 - 360 WP_077253379.1 tyrosine-type recombinase/integrase -
G7Z27_RS09870 2007578..2008057 + 480 WP_032419797.1 lysis protein -
G7Z27_RS09875 2008846..2010351 + 1506 WP_020956680.1 hypothetical protein -
G7Z27_RS09880 2010601..2011029 - 429 WP_032419788.1 type II toxin-antitoxin system PemK/MazF family toxin -
G7Z27_RS09885 2011039..2011320 - 282 WP_032419786.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T151439 NZ_CP049716:2006985-2007087 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT151439 NZ_CP049716:c2007093-2006949 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References