Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 670428..670959 Replicon chromosome
Accession NZ_CP049684
Organism Polynucleobacter paneuropaeus strain AP-Creno-5A-D2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C2742_RS03485 Protein ID WP_112203740.1
Coordinates 670428..670709 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag C2742_RS03490 Protein ID WP_112203742.1
Coordinates 670696..670959 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2742_RS03470 (C2742_03475) 667788..668291 + 504 WP_112237935.1 DUF1993 domain-containing protein -
C2742_RS03475 (C2742_03480) 668312..669268 - 957 WP_112294736.1 tripartite tricarboxylate transporter substrate binding protein -
C2742_RS03480 (C2742_03485) 669265..670332 - 1068 WP_215279025.1 tartrate dehydrogenase -
C2742_RS03485 (C2742_03490) 670428..670709 - 282 WP_112203740.1 type II toxin-antitoxin system YafQ family toxin Toxin
C2742_RS03490 (C2742_03495) 670696..670959 - 264 WP_112203742.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
C2742_RS03495 (C2742_03500) 671074..671559 + 486 WP_112209114.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
C2742_RS03500 (C2742_03505) 671556..672845 + 1290 WP_215279026.1 Y-family DNA polymerase -
C2742_RS08425 672872..673006 + 135 WP_255880031.1 hypothetical protein -
C2742_RS03505 (C2742_03510) 673176..673595 + 420 WP_215279027.1 Smr/MutS family protein -
C2742_RS08430 673750..673881 + 132 WP_285895772.1 hypothetical protein -
C2742_RS03510 (C2742_03515) 673907..674440 + 534 WP_215279028.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-76)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11474.14 Da        Isoelectric Point: 9.2930

>T151419 WP_112203740.1 NZ_CP049684:c670709-670428 [Polynucleobacter paneuropaeus]
MRTTEYTKKFRKDYKRELKGRYRLTLARDFQETLDYLINDWDLPYRYHDHPLVGDWVDHRDCHIKPDLVLIYRKPDQRIL
QLVRLGSHSELSL

Download         Length: 282 bp

>T151419 NZ_CP065464:c3305812-3305710 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9362.78 Da        Isoelectric Point: 5.0651

>AT151419 WP_112203742.1 NZ_CP049684:c670959-670696 [Polynucleobacter paneuropaeus]
MTANAVVRARINGDIKEEASAILAAMGLTPSDAFRILMTRIAREKALPFEPLSPNAETIAAMKEARKGNLKSFTSVNDLM
ADLNADD

Download         Length: 264 bp

>AT151419 NZ_CP065464:3305703-3305848 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References