151395

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 3140413..3140994 Replicon chromosome
Accession NZ_CP049616
Organism Muricauda sp. 501str8

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag GVT53_RS14320 Protein ID WP_166249185.1
Coordinates 3140695..3140994 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GVT53_RS14315 Protein ID WP_166249184.1
Coordinates 3140413..3140691 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GVT53_RS14280 3135509..3135856 + 348 WP_166249178.1 OmpA family protein -
GVT53_RS14285 3135874..3136566 + 693 WP_166249179.1 hypothetical protein -
GVT53_RS14290 3136618..3137286 - 669 WP_166249180.1 hypothetical protein -
GVT53_RS14295 3137429..3138145 - 717 WP_166249181.1 lipoyl(octanoyl) transferase LipB -
GVT53_RS14300 3138178..3138915 - 738 WP_166249182.1 hypothetical protein -
GVT53_RS14305 3139099..3139254 - 156 WP_090291467.1 YqaE/Pmp3 family membrane protein -
GVT53_RS14310 3139348..3140388 + 1041 WP_166249183.1 response regulator transcription factor -
GVT53_RS14315 3140413..3140691 - 279 WP_166249184.1 putative addiction module antidote protein Antitoxin
GVT53_RS14320 3140695..3140994 - 300 WP_166249185.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GVT53_RS14325 3141207..3141749 + 543 WP_166249186.1 thioredoxin family protein -
GVT53_RS14330 3141815..3143506 + 1692 WP_166249187.1 lysine--tRNA ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-98)

Antitoxin

Uncharacterized protein HI1420

(3-89)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11683.74 Da        Isoelectric Point: 10.9705

>T151395 WP_166249185.1 NZ_CP049616:c3140994-3140695 [Muricauda sp. 501str8]
MFFIEKTVEFDRWLRRLKDIRAKAKILFRIQRIENDGHFGDCKSVGNGISEIRIHFAKGYRVYFKEKNGRIIVLLAGGDK
SSQKRDIKKAKEIWNKLKA

Download         Length: 300 bp

>T151395 NZ_CP065457:c4526574-4526206 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCAGCGAATCCAGACTTCGTCGGTATTACCGTCGAGGCAGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGTGGATGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 9899.34 Da        Isoelectric Point: 4.7628

>AT151395 WP_166249184.1 NZ_CP049616:c3140691-3140413 [Muricauda sp. 501str8]
METSKFDIADYLDSKEMIAEYLNTVLEEGDSGDVVNAIGHIAKAIGMTKISEETGLSRPSLYKALSDGSKPQFATIMKVL
KAIGGQVQVHPV

Download         Length: 279 bp

>AT151395 NZ_CP065457:c4526792-4526571 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCTGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References