Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2438969..2439203 Replicon chromosome
Accession NZ_CP049606
Organism Shigella boydii strain 600080

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2438970..2439073 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2438969..2439203 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G5S61_RS12325 2434513..2434785 + 273 WP_001277358.1 host-nuclease inhibitor Gam family protein -
G5S61_RS12330 2434815..2435912 + 1098 WP_039066158.1 AAA family ATPase -
G5S61_RS12335 2435963..2436151 + 189 WP_000276807.1 DUF1187 family protein -
- 2435969..2436147 - 179 NuclAT_0 - -
- 2435969..2436147 - 179 NuclAT_0 - -
- 2435969..2436147 - 179 NuclAT_0 - -
- 2435969..2436147 - 179 NuclAT_0 - -
G5S61_RS12340 2436252..2437408 + 1157 WP_178986836.1 IS3-like element IS600 family transposase -
G5S61_RS12345 2437525..2437806 + 282 WP_005127484.1 excisionase -
G5S61_RS12350 2437772..2438848 + 1077 WP_001189100.1 phage integrase Arm DNA-binding domain-containing protein -
- 2438969..2439203 + 235 - - Antitoxin
- 2438970..2439073 - 104 - - Toxin
G5S61_RS12355 2439231..2439572 - 342 WP_073705566.1 YebY family protein -
G5S61_RS12360 2439585..2440457 - 873 WP_039066159.1 copper homeostasis membrane protein CopD -
G5S61_RS12365 2440461..2440835 - 375 WP_000168747.1 CopC domain-containing protein YobA -
G5S61_RS12370 2440974..2441204 + 231 WP_000916763.1 DNA polymerase III subunit theta -
G5S61_RS12375 2441306..2441962 + 657 Protein_2452 carbon-nitrogen hydrolase family protein -
G5S61_RS12380 2441986..2442648 + 663 WP_000944270.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2417169..2439572 22403


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T151368 NZ_CP049606:c2439073-2438970 [Shigella boydii]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT151368 NZ_CP049606:2438969-2439203 [Shigella boydii]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References