Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4263446..4263591 Replicon chromosome
Accession NZ_CP049604
Organism Klebsiella pneumoniae strain Kp8701

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4263453..4263555 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4263446..4263591 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G7L41_RS21360 4258977..4260410 + 1434 WP_048292090.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
G7L41_RS21365 4260526..4260765 + 240 WP_002911393.1 YebV family protein -
G7L41_RS21370 4260863..4261054 + 192 WP_002911395.1 YebW family protein -
G7L41_RS21375 4261051..4261704 - 654 WP_023280291.1 protein-serine/threonine phosphatase -
G7L41_RS21380 4261861..4262829 + 969 WP_004151446.1 VirK/YbjX family protein -
G7L41_RS21385 4262934..4263077 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4263446..4263591 + 146 - - Antitoxin
- 4263453..4263555 - 103 - - Toxin
G7L41_RS21390 4263714..4264052 - 339 WP_016529031.1 YebY family protein -
G7L41_RS21395 4264069..4264938 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
G7L41_RS21400 4264942..4265316 - 375 WP_004151448.1 CopC domain-containing protein YobA -
G7L41_RS21405 4265429..4265659 + 231 WP_002911406.1 DNA polymerase III subunit theta -
G7L41_RS21410 4265738..4266397 + 660 WP_002911407.1 exodeoxyribonuclease X -
G7L41_RS21415 4266401..4268461 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T151347 NZ_CP049604:c4263555-4263453 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT151347 NZ_CP049604:4263446-4263591 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References