Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1955883..1956154 Replicon chromosome
Accession NZ_CP049353
Organism Escherichia coli strain T28R

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1956013..1956116 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1955883..1956154 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G7B60_RS09415 1952438..1953100 - 663 WP_000944256.1 exodeoxyribonuclease X -
G7B60_RS09420 1953124..1953780 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
G7B60_RS09425 1953882..1954112 - 231 WP_000916763.1 DNA polymerase III subunit theta -
G7B60_RS09430 1954251..1954625 + 375 WP_000168747.1 CopC domain-containing protein YobA -
G7B60_RS09435 1954629..1955501 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
G7B60_RS09440 1955514..1955855 + 342 WP_000976476.1 YebY family protein -
- 1955883..1956154 - 272 - - Antitoxin
- 1956013..1956116 + 104 - - Toxin
G7B60_RS09445 1956251..1956907 + 657 WP_000812720.1 protein-serine/threonine phosphatase -
G7B60_RS09450 1956908..1957099 - 192 WP_001296140.1 YebW family protein -
G7B60_RS09455 1957204..1957440 - 237 WP_001295499.1 DUF1480 family protein -
G7B60_RS09460 1957558..1958997 - 1440 WP_024174420.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T151289 NZ_CP049353:1956013-1956116 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT151289 NZ_CP049353:c1956154-1955883 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References