Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 1469896..1470434 Replicon plasmid pSBC2-2
Accession NZ_CP049318
Organism Caballeronia sp. SBC2

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag SBC2_RS33200 Protein ID WP_165104579.1
Coordinates 1469896..1470195 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag SBC2_RS33205 Protein ID WP_165104580.1
Coordinates 1470192..1470434 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SBC2_RS33180 1465242..1465958 + 717 WP_165104575.1 2Fe-2S iron-sulfur cluster binding domain-containing protein -
SBC2_RS33185 1465968..1466957 + 990 WP_165104576.1 xanthine dehydrogenase family protein subunit M -
SBC2_RS33190 1466954..1469182 + 2229 WP_165104577.1 xanthine dehydrogenase family protein molybdopterin-binding subunit -
SBC2_RS33195 1469302..1469889 + 588 WP_165104578.1 nucleotidyltransferase family protein -
SBC2_RS33200 1469896..1470195 - 300 WP_165104579.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SBC2_RS33205 1470192..1470434 - 243 WP_165104580.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
SBC2_RS33210 1470616..1471311 - 696 WP_165104581.1 glycosyltransferase -
SBC2_RS33215 1471726..1472178 - 453 WP_165104582.1 DUF2442 domain-containing protein -
SBC2_RS33220 1472175..1472594 - 420 WP_165104583.1 DUF4160 domain-containing protein -
SBC2_RS33225 1472846..1473343 + 498 WP_165104584.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - adeG / gnd 1..1831039 1831039


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-71)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11569.43 Da        Isoelectric Point: 10.2789

>T151205 WP_165104579.1 NZ_CP049318:c1470195-1469896 [Caballeronia sp. SBC2]
MTYKLRFKLNAEKEWRKLDAETRRQFAKKLDLRLENPKVPASRLHGMKDCYKIKLRTRGYRLVYQVQDEIVTVVVIAVGK
RDGGVVHDAAEERAAEEPQ

Download         Length: 300 bp

>T151205 NZ_CP065374:5449366-5449953 [Pseudomonas aeruginosa]
ATGTCGAGGAGGGCGCCCATGTTCAAGCCGCTACCGATCACCCTGCAGCGCGGAGCCTTGCGTCTCGAGCCGCTGGTGGA
AGCGGACATTCCCGAGCTGGTGAGCCTCGCCGAAGCCAACCGCGAGGCGCTGCAGTACATGGACGGACCGACGCGGCCGG
ACTGGTACCGCCAGAGCCTCGCCGAGCAGCGCGAGGGCAGGGCGTTGCCGCTCGCCGTCCGCCTCGGCGTGCAACTGGTC
GGGACCACGCGCTTCGCCGAGTTCCTTCCCGCCTTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGACCAGGCCCAGCA
CGGCAGCGGCCTGAACCGCATGATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACCTGCGCATGGTCCGCGTGCAGC
TCAGCACGGCGGCGAGCAACCTGCGCGCCCAGGGCGCCATCGACAAGCTCGGCGCGCAGCGCGAGGGCGTGCTGCGCAAC
CACCGGCGGCTGGCCGGCGGGCGGCTAGACGACACCTTCGTCTACAGCATCACCGACCACGAATGGCCGCAGGTCAAGGC
GGCGCTGGAAGCCAGCTTCACCGGCTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8808.02 Da        Isoelectric Point: 4.3210

>AT151205 WP_165104580.1 NZ_CP049318:c1470434-1470192 [Caballeronia sp. SBC2]
MEAIHATQSVGISELKLNPTAVIESADGGAVAILNRNKPVAYLLPAEQYEALLDRLEDFELAEIVRARQNEPLVEVDIHK

Download         Length: 243 bp

>AT151205 NZ_CP065374:5450020-5450874 [Pseudomonas aeruginosa]
GTGCCGGACGAGACGAGCGGAGAACACACGCATTTCTGGCGCGCCGCCGAACTGGGCGGCGTCGAACTGCTGCACGCGCG
CTATGTGGAGCAGCGCTTCGCGCCGCACGTGCACAGCAGCTTCGCCCTAGTCATCATCGAGCAGGGCGCGCAGCGCTTCC
GCCATCGTGGCGGCGAGCACCTAGCCCCGCTGGGCAGCATGGTGCTGATCAACCCCGACGAAGTGCACACCGGCTCCAAG
GCCCATGATGCCGGTTGGCTCTATCGCGGCTACTACCCGGAAATGGAACAGATCGACGGGATTCTCGACGAGCTGGAAAT
CCATCATGGCGGCGTGCCGCGTTTCGCCGACAGCGTGATCCACGACCAGCCCCTGGCACGCGCCTTCGTCCACTTGCACC
GCCTGCTGGCCGAGCATGCCGGCAGCCTGGAAACCCAGACCCGCTGGCGCGAGACGATGCTCGCCCTGTTCCGTCGCCAC
GCCCGCCTGCCAGAAGCGCCGAAGGCCGGGCAGGAGCCGTTGGCGGTGGCCCGCGCCCGCGAACTGCTGGCGGCGCGGTT
GCTCGATCCGCCTTCTCTGGAGGAACTGGCGGCGGCGGTCAATCTGTCCCCGTTCCATTTTGCCCGGGTCTTCCGTCGCG
CCACCGGCATGCCGCCCCACGCCTGGCTCAGACAGCGCCGCCTGGAGCAGGCCAGGGCACTGCTCAAGAGCGGCCGGGCG
CCGCTGGAGGTGGCCCTGGAGCTGGGCTTCGCCGACCAGAGCCACCTCGGTCGCCAGTTCAAGCAGGCCTACGGGGTGGC
ACCGGGTGAATACCGCTCGGCCTGCGCGCGCTCGTCCTTGACGACATACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References