Detailed information of TA system TA151197

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/upstrm_HI1419-dnstrm_HI1420
• Location: 1458389..1458987
• Replicon: chromosome
• Accession: NZ_CP049316
• Organism: Caballeronia sp. SBC2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SBC2_RS06295
• Protein ID: WP_165088423.1
• Coordinates: 1458679..1458987 (-)
• Length: 103 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: SBC2_RS06290
• Protein ID: WP_165088420.1
• Coordinates: 1458389..1458682 (-)
• Length: 98 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SBC2_RS06275	1454481..1455626	+	1146	WP_165088410.1	PAS domain-containing sensor histidine kinase	-
SBC2_RS06280	1455771..1457276	+	1506	WP_165088414.1	nitrogen regulation protein NR(I)	-
SBC2_RS06285	1457453..1458229	-	777	WP_165088417.1	exodeoxyribonuclease III	-
SBC2_RS06290	1458389..1458682	-	294	WP_165088420.1	putative addiction module antidote protein	Antitoxin
SBC2_RS06295	1458679..1458987	-	309	WP_165088423.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SBC2_RS06300	1459284..1460558	+	1275	WP_165088428.1	amidohydrolase family protein	-
SBC2_RS06305	1460699..1461316	-	618	WP_165088431.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Addiction module killer protein, predicted (4-96)

Antitoxin

• Cro/C1-type helix-turn-helix domain (39-90)

Sequences

Toxin

Protein

• Length: 103 a.a.
• Molecular weight: 11480.23 Da
• Isoelectric Point: 10.6682

>T151197 WP_165088423.1 NZ_CP049316:c1458987-1458679 [Caballeronia sp. SBC2]
MTNTINQTHDFSVWLLGVTDVLARAAILIRIKRAALGNFGDCHDVGSSVWEMRIHTGAGYRVYYVRDGSTVYLLLAGGSK
RGQISDIARAKAMWQRIRQERK

Nucleotide

• Length: 309 bp

>T151197 NZ_CP065369:809560-809862 [Vibrio parahaemolyticus]
ATGGCTGAAATAATCTGGACTGAGCCAGCGCTATCTGATCTCAATGATATCGCTGAATATATCGCACTTGAAAATATCGT
AGCTGCAAAACAATTGGTTCAAGCGATCTTTTCTAAAGTTGAGCGCTTAGTGGCTTTCCCTGAATCGGGTCGCATTCCAC
CTGAACTAGCACATCTAAGTTATCGTGAAGTTGTCGTTAATCCGTGCCGTATTTTCTATAAACAAGACGGCGACAAAGTA
TTTATTCTGTTTGTTATGCGTGCTGAGAGAGACTTACGTAAGTTCCTATTGAGCAAGCAATAA

Antitoxin

Protein

• Length: 98 a.a.
• Molecular weight: 10187.53 Da
• Isoelectric Point: 5.0484

>AT151197 WP_165088420.1 NZ_CP049316:c1458682-1458389 [Caballeronia sp. SBC2]
MNSTHISAFDASDYLDSEEAIAAYLNEALASGDSDILLSALADIVKARGMSKVASDAGVQRESLYKSLAEGAKPRFETIQ
KVAAALGVKLVAVPVHH

Nucleotide

• Length: 294 bp

>AT151197 NZ_CP065369:809315-809572 [Vibrio parahaemolyticus]
ATGAAAGTAGAACTAGTTACATCACTTAAACGTCAAGCAACTAAGATCCTCGCCGATCTTCACGACACCAAAGAACCAGT
GTTAATTACTGAACATGGTAAGCCATCGGCATATCTGGTTGATGTTGATGATTACGAGTTTATGCAAAATCGCTTGGCGA
TTCTGGAGGGGATTGCACGAGGTGAACGTGCATTAGCTGACGGTAAAGTGGTGAGTCACGATGAAGCCAAGGACAAAATG
TCAAAATGGCTGAAATAA