Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 694577..694973 Replicon chromosome
Accession NZ_CP049316
Organism Caballeronia sp. SBC2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SBC2_RS03025 Protein ID WP_165086719.1
Coordinates 694761..694973 (+) Length 71 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag SBC2_RS03020 Protein ID WP_165086717.1
Coordinates 694577..694771 (+) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SBC2_RS02995 690413..691312 + 900 WP_165086697.1 ParB N-terminal domain-containing protein -
SBC2_RS03000 692088..692333 + 246 WP_165086701.1 hypothetical protein -
SBC2_RS03005 692418..693110 + 693 WP_206365996.1 pentapeptide repeat-containing protein -
SBC2_RS03010 693122..693412 + 291 WP_165086708.1 hypothetical protein -
SBC2_RS03015 694106..694300 + 195 WP_165086712.1 hypothetical protein -
SBC2_RS03020 694577..694771 + 195 WP_165086717.1 antitoxin Antitoxin
SBC2_RS03025 694761..694973 + 213 WP_165086719.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SBC2_RS03030 695042..695305 + 264 WP_165086722.1 hypothetical protein -
SBC2_RS03035 697048..697443 - 396 WP_165086724.1 hypothetical protein -
SBC2_RS03040 698297..698617 + 321 WP_165086727.1 hypothetical protein -
SBC2_RS03045 699167..699370 + 204 WP_165086729.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-70)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 71 a.a.        Molecular weight: 8080.41 Da        Isoelectric Point: 6.4579

>T151196 WP_165086719.1 NZ_CP049316:694761-694973 [Caballeronia sp. SBC2]
MLVEWQPRALRRLDAIHKRIQEESVTAADFVFEAIVAAAAALLDHPYIYREGRVPNIREMAVLPNYIVVY

Download         Length: 213 bp

>T151196 NZ_CP065369:c771005-770709 [Vibrio parahaemolyticus]
ATGCAAAAGAATAAATACAAACTAAGTAAATTAGCTCAGGCTCATTTAATAAAAATCAAAAACTACACCGTTAATAACTT
TTCAGAGATGCAGTGGCGCAACTACAAAGATACGTTACTAACTGGGTTTCAGATGCTTGCTGACAATCCGGAAGTTGGTA
GAAGTTGCGATGACATTTACCCAAACGGGTTTCACTTTCCTGTTGGTAAGCACACAGCTTACTTTACAAAAGAAGACGGC
TTCATTTTGGTTGTAGCTGTACTCGGTCAGTCACAATTACCGCAAAACCACTTATGA

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7299.00 Da        Isoelectric Point: 4.3077

>AT151196 WP_165086717.1 NZ_CP049316:694577-694771 [Caballeronia sp. SBC2]
MSKIPIDPALTEHSSLEEAQAYDAWFRAEVQASLDEDAPSVPHDEAVAEMREYIEQRKQARNAR

Download         Length: 195 bp

>AT151196 NZ_CP065369:c771254-771012 [Vibrio parahaemolyticus]
ATGCACACATTAACGGCAAATGATGCGAAACGTAATTTTGGTGAACTTCTTCTGAGCGCCCAACGTGAGCCAGTAAAAAT
TAGCAAAAACAGTAAAGACGCCGTAGTTGTAATGTCTATTAAAGATTATGAAGAGCTAGAAGCTATGAAAGCTGATTACC
TTAAACATTGCTTTGAATCCGCGAAAAAAGACTTAGCGCAAGGCAATGTGGTTGATGGTGAAGACTTCTTGAGCGCCTTG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References