Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 518029..518576 Replicon chromosome
Accession NZ_CP049298
Organism Chryseobacterium sp. POL2

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag G6R40_RS02380 Protein ID WP_165131134.1
Coordinates 518029..518328 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag G6R40_RS02385 Protein ID WP_165131196.1
Coordinates 518328..518576 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6R40_RS02365 513741..514253 - 513 WP_165131192.1 hypothetical protein -
G6R40_RS02370 514543..516117 + 1575 WP_165131100.1 IS1182 family transposase -
G6R40_RS02375 516444..517094 - 651 WP_165131194.1 hypothetical protein -
G6R40_RS02380 518029..518328 - 300 WP_165131134.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6R40_RS02385 518328..518576 - 249 WP_165131196.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
G6R40_RS02390 518857..519363 - 507 WP_165131198.1 MepB family protein -
G6R40_RS02395 519600..520190 - 591 WP_165131200.1 hypothetical protein -
G6R40_RS02400 520424..521251 - 828 WP_165131147.1 GLPGLI family protein -
G6R40_RS02405 521274..521423 + 150 WP_165131202.1 hypothetical protein -
G6R40_RS02410 521716..522933 + 1218 WP_165131060.1 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 12257.86 Da        Isoelectric Point: 4.7620

>T151192 WP_165131134.1 NZ_CP049298:c518328-518029 [Chryseobacterium sp. POL2]
MNYKISKQAEIDLENIWLYTFEEWSIEQADYYFDLIMDEIEYISKNPKSGKDYNEIRKGYFRSRVKSHFIFYRINFKEEC
IEIIRILHQQMDVESHIND

Download         Length: 300 bp

>T151192 NZ_CP065367:c1300187-1299873 [Vibrio cyclitrophicus]
ATGGCTGTAATTAATTGGACTGAATCAGCATTATTAGATTTGGACGAAATTGCAGAATATATCGCTATTAATAATATTTT
AGCGGCTAAGGCTTTAGTTCAATCAGTTTTCCATCGTGTTGAGCGTTTAGAGGATTTTCCATTATCAGGCCGTAGTGCTC
CTGAGCTTCCTCATTTAGATTATCGTGAAATTGTATTACCGCCATGCCGTATTTTTTACAAAGTAACCAACGATGATATT
GTATATATTCTTTATGTCATGAGGGAAGAGCGCGAGTTACGCCAATTTGTTCTCAATGACCGTGGTTTGCAGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9425.62 Da        Isoelectric Point: 9.7995

>AT151192 WP_165131196.1 NZ_CP049298:c518576-518328 [Chryseobacterium sp. POL2]
MAKNTSILLGDYFDNFINSQIKNGKYSSASEVVRAALRMFEHEETKKSELIKELKKGEKSGFSASFNRETFKQNLHQKYS
AE

Download         Length: 249 bp

>AT151192 NZ_CP065367:c1300432-1300178 [Vibrio cyclitrophicus]
ATGAAAGTTGAGCTAGTTACTACATTAAAACGTCAAGCAACCAAGATTCTTTCTGAGCTTCATGCTTCAAAAGAACCAGT
GTTAATTACAGAGCACGGCCAACCGTCTGCTTATTTGTTAGATGTTGATGATTACGAGTTTATGCAAAAACGTATTGCTA
TTCTTGAAGGTATTGCTCGCGGTGAAAAAGCAATTTCAGATAATCGTGTAGTTTCTCATGAAGTCGCAAAAGAGAAGATG
AATAAATGGCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References