Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 476711..477258 Replicon chromosome
Accession NZ_CP049298
Organism Chryseobacterium sp. POL2

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag G6R40_RS02175 Protein ID WP_165131134.1
Coordinates 476711..477010 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag G6R40_RS02180 Protein ID WP_165131136.1
Coordinates 477010..477258 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6R40_RS02155 472339..473109 - 771 WP_165131126.1 hypothetical protein -
G6R40_RS02160 473128..473658 - 531 WP_165131128.1 hypothetical protein -
G6R40_RS02165 474150..475313 - 1164 WP_165131130.1 DUF262 domain-containing protein -
G6R40_RS02170 475314..476411 - 1098 WP_165131132.1 DNA methyltransferase -
G6R40_RS02175 476711..477010 - 300 WP_165131134.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6R40_RS02180 477010..477258 - 249 WP_165131136.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
G6R40_RS02185 477605..479179 + 1575 WP_165131100.1 IS1182 family transposase -
G6R40_RS02190 479292..479870 - 579 WP_165131138.1 hypothetical protein -
G6R40_RS02195 480122..480589 - 468 WP_165131140.1 hypothetical protein -
G6R40_RS02200 480842..481630 - 789 WP_165131142.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 12257.86 Da        Isoelectric Point: 4.7620

>T151191 WP_165131134.1 NZ_CP049298:c477010-476711 [Chryseobacterium sp. POL2]
MNYKISKQAEIDLENIWLYTFEEWSIEQADYYFDLIMDEIEYISKNPKSGKDYNEIRKGYFRSRVKSHFIFYRINFKEEC
IEIIRILHQQMDVESHIND

Download         Length: 300 bp

>T151191 NZ_CP065367:c209985-209695 [Vibrio cyclitrophicus]
ATGACCTATAAACTCGACTTTAAAAAGAGCGCACTCAAAGAGTGGAAAAAGCTTGGCTCAACGCTTCAACAACAATTTAA
GAAAAAGCTAATCGAGCGCTTAGATAACCCGCATGTTCCGGCTTCAAAACTCTCTGGAGCTGACAACATGTATAAGATTA
AGCTTCGCCAATCGGGCTACCGTCTCGTCTACAAAGTTGAAGACGATGTCATCATTGTAACCGTCTTAGCAGTCGGAAAA
CGCGAACGTAGCGATGTTTACCGTAAAGCGATGAAAAGGTTAGATGATTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9395.59 Da        Isoelectric Point: 9.7995

>AT151191 WP_165131136.1 NZ_CP049298:c477258-477010 [Chryseobacterium sp. POL2]
MAKNTSILLGDYFDNFINSQIKNGKYSSASEVVRAALRMFEHEEAKKSELIKELKKGEKSGFSASFNRETFKQNLHQKYS
AE

Download         Length: 249 bp

>AT151191 NZ_CP065367:c210223-209975 [Vibrio cyclitrophicus]
ATGACCGCTAGAATTTTAGCCGATGTTGCTGCAAGCATTACTGAGTTGAAAGCTAACCCTATGAAAGTTGCAACTAGTGC
TTACGGTGAACCTGTTGCTGTACTGAACCGAAATGAGCCAGCATTTTATTGCGTACCAGCCGAAGCGTACGAAATGATGA
TGGACAGACTCGAAGATCTTGAACTACTAACTATTGCGAAAGAGCGTGAATCTGAAGAGAGCATTTCGGTAAATATTGAT
GACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References