Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2193614..2193848 Replicon chromosome
Accession NZ_CP049278
Organism Shigella boydii strain 600690

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2193744..2193847 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2193614..2193848 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G5S56_RS10635 2190169..2190831 - 663 WP_000944257.1 exodeoxyribonuclease X -
G5S56_RS10640 2190855..2191511 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
G5S56_RS10645 2191613..2191843 - 231 WP_000916763.1 DNA polymerase III subunit theta -
G5S56_RS10650 2191982..2192356 + 375 WP_000168747.1 CopC domain-containing protein YobA -
G5S56_RS10655 2192360..2193232 + 873 WP_000879303.1 copper homeostasis membrane protein CopD -
G5S56_RS10660 2193245..2193586 + 342 WP_000976480.1 YebY family protein -
- 2193614..2193848 - 235 - - Antitoxin
- 2193744..2193847 + 104 - - Toxin
G5S56_RS10665 2193969..2195008 - 1040 Protein_2083 phage integrase Arm DNA-binding domain-containing protein -
G5S56_RS10670 2195227..2196383 + 1157 WP_134795703.1 IS3-like element IS600 family transposase -
G5S56_RS10675 2196425..2196931 + 507 Protein_2085 transposase -
G5S56_RS10680 2196978..2197160 + 183 WP_001224662.1 hypothetical protein -
G5S56_RS10685 2197153..2197329 + 177 WP_000753060.1 hypothetical protein -
G5S56_RS25180 2197326..2197654 + 329 Protein_2088 hypothetical protein -
G5S56_RS10695 2197953..2198240 - 288 WP_000090004.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - ipaH9.8 2188112..2217567 29455


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T151113 NZ_CP049278:2193744-2193847 [Shigella boydii]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT151113 NZ_CP049278:c2193848-2193614 [Shigella boydii]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCAGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References