Detailed information of TA system TA151098

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 96276..96804
• Replicon: chromosome
• Accession: NZ_CP049272
• Organism: Campylobacter concisus strain P27CDO-S2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CVT17_RS00440
• Protein ID: WP_107858789.1
• Coordinates: 96276..96563 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CVT17_RS00445
• Protein ID: WP_103609401.1
• Coordinates: 96553..96804 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CVT17_RS00415	91430..92093	+	664	Protein_80	replisome organizer	-
CVT17_RS00420	92201..93038	+	838	Protein_81	ATP-binding protein	-
CVT17_RS00425	93100..93273	+	174	WP_009295461.1	transposon-encoded TnpW family protein	-
CVT17_RS00430	93941..95533	-	1593	WP_107858791.1	relaxase/mobilization nuclease domain-containing protein	-
CVT17_RS00435	95581..95910	-	330	WP_107858790.1	hypothetical protein	-
CVT17_RS00440	96276..96563	-	288	WP_107858789.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CVT17_RS00445	96553..96804	-	252	WP_103609401.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
CVT17_RS00450	96887..98668	-	1782	WP_107858788.1	site-specific integrase	-
CVT17_RS00455	99551..99793	+	243	WP_159070455.1	hypothetical protein	-
CVT17_RS00460	99786..100274	+	489	WP_107858787.1	hypothetical protein	-
CVT17_RS00465	100357..101055	+	699	WP_107769945.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	33659..99006	65347

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-77)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11332.21 Da
• Isoelectric Point: 9.7349

>T151098 WP_107858789.1 NZ_CP049272:c96563-96276 [Campylobacter concisus]
MSYELEFLPSALKEWQKLDNSIKVQFKKKLSERLENPKVTKDKLRGYEDVYKIKLRDVGYRLAYQVKDSEIVVLVLVVGK
RENNEVYEMLKDKFS

Nucleotide

• Length: 288 bp

>T151098 NZ_CP065233:c3068119-3067838 [Alteromonas sp. B31-7]
ATGATCTTATGGGAAAAAAGTTCGTTGGACGATCGTGAGGCTATTTTCGAATTTTTATACGAATTTAACCCATTAGCAGC
AGAACAAACTGATGCAATAATAGAGAAGAAAGTTGAAAACTTGAACCAGCAACCTCTTATGGGAGTAGAGAGAGAGGGTA
TACCGGGAAGATTGTTAATAATTCCAGAGCTTTCAATGATTGTTTCATATTTCAGAAAAGACGACATTATTCACATTCTT
CGAGTTTTACACCAAAAGCAAAAATTTCCTGTAGGCAACTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9035.42 Da
• Isoelectric Point: 4.9901

>AT151098 WP_103609401.1 NZ_CP049272:c96804-96553 [Campylobacter concisus]
MQTIQANFTASISELKKSPAQILKQAGDNVVAILNHNVPSAYLVPSAVYEKMIEIIEEYHLNKAVDAALVSGEKPVKVSL
DEL

Nucleotide

• Length: 252 bp

>AT151098 NZ_CP065233:c3068400-3068116 [Alteromonas sp. B31-7]
ATGGATACCCGTATTCAGTTTAGAGTAGATGAAGAAACTAAACGGCTAGCTCAGACAATGGCCGAAAGCCAAGGACGCAC
TTTAAGTGACGCTTGTAGAGAGCTTACGGAAGAACTCGCTGAACAGCAACGAAAAATAATTACTCATGATCAGTGGCTTA
CTGAAGAGATTAATGCCGCGTTCAGTAAATTAGAGAGTGGGCAAAGCAAGTTCATCAGTCATGAAGAAGCGAACTTGGAC
ATGGAAGCTCGAAAAATGAAAATTAGGAATAAAGCCAAAAAATGA