Detailed information of TA system TA151097

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 53406..53940
• Replicon: chromosome
• Accession: NZ_CP049270
• Organism: Campylobacter concisus strain P26UCO-S2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CVT15_RS00250
• Protein ID: WP_103576526.1
• Coordinates: 53406..53699 (-)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CVT15_RS00255
• Protein ID: WP_103576527.1
• Coordinates: 53689..53940 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CVT15_RS00235	49314..50180	-	867	WP_103577259.1	flagellar biosynthesis protein FlgG	-
CVT15_RS00240	51075..52667	-	1593	WP_103577242.1	relaxase/mobilization nuclease domain-containing protein	-
CVT15_RS00245	52715..53044	-	330	WP_103577241.1	plasmid mobilization relaxosome protein MobC	-
CVT15_RS00250	53406..53699	-	294	WP_103576526.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CVT15_RS00255	53689..53940	-	252	WP_103576527.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
CVT15_RS00260	54022..55803	-	1782	WP_103576528.1	site-specific integrase	-
CVT15_RS00265	56562..57494	+	933	WP_103576529.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	42040..69466	27426

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-74)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 11438.32 Da
• Isoelectric Point: 9.8989

>T151097 WP_103576526.1 NZ_CP049270:c53699-53406 [Campylobacter concisus]
MSYELEFLPSALKEWQKLDNSIKVQFKKKLSERLENPKVAKDKLRGYGDVYKIKLRDVGYRLAYQVKDSEIVVLVLVVGK
RENNEVYEILKDKFNQA

Nucleotide

• Length: 294 bp

>T151097 NZ_CP065233:c2901306-2901028 [Alteromonas sp. B31-7]
ATGATTAAGGGTTTTATACATAAAGGCCTTCAGAAGTTTTACGCTAAAGGAACCACTTCAGAAATTCAGAAAAAGCACGA
AAAAAAGCTTCGTCTTATTCTGTCGAATCTCGATCAAGCCGAAACACCTGATGACATGGATTTACCCGGCCTTTATATGC
ACAAACTCAAAGGTAACAGAAATGATATTTGGTCTGTTCAGGTAAGTGGAAACTGGAGAGTTACATACCGCTTTGTTGGA
CGAGATGTTGAAATCGTTAATTACGAGGATTATCACTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 8996.30 Da
• Isoelectric Point: 4.6982

>AT151097 WP_103576527.1 NZ_CP049270:c53940-53689 [Campylobacter concisus]
MQTIQANFTASISELKKSPAQILKQAGDNVVAILNHNVPSAYLVPSAVYEKMAEIIEEYHLSKAVDAALASDEKPVKVSL
DEL

Nucleotide

• Length: 252 bp

>AT151097 NZ_CP065233:c2901028-2900732 [Alteromonas sp. B31-7]
ATGAATATGCATAACCCTGCGCATCCCGGTGAGATACTCAAAGATCTTGTTATTGATGCTCTAGAACTGACTATTACTGA
TGTAGCGCAACATTTAGATGTGAGCCGTAAAACATTATCGAAAGTTCTTAATGGCAAAGGGGCTATTACCCCAGAGATGG
CTCTTCGTCTTGAACTCGTTTTCGGTAAGCCTTCTGCGGCCCATTGGCTTCGTTTGCAAAATGCATTTGATTTGTGGCAA
ACAAGACAATATCAAAGCTCTTTACATGTCTCACCGTATAATTTGGCTACGGTATAA