Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) NpoTA/ParE(toxin)
Location 4971487..4972728 Replicon chromosome
Accession NZ_CP049258
Organism Nordella sp. HKS 07

Toxin (Protein)


Gene name NpoT Uniprot ID -
Locus tag G5V57_RS23340 Protein ID WP_165169927.1
Coordinates 4972486..4972728 (+) Length 81 a.a.

Antitoxin (Protein)


Gene name NpoA Uniprot ID -
Locus tag G5V57_RS23335 Protein ID WP_165169926.1
Coordinates 4971487..4972473 (+) Length 329 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G5V57_RS23320 4967120..4968385 - 1266 WP_165174232.1 MFS transporter -
G5V57_RS23325 4968817..4970523 + 1707 WP_165169924.1 HAD hydrolase family protein -
G5V57_RS23330 4971213..4971407 + 195 WP_165169925.1 hypothetical protein -
G5V57_RS23335 4971487..4972473 + 987 WP_165169926.1 SDR family oxidoreductase Antitoxin
G5V57_RS23340 4972486..4972728 + 243 WP_165169927.1 plasmid stabilization protein Toxin
G5V57_RS23345 4973109..4973609 - 501 WP_165169928.1 ferritin-like domain-containing protein -
G5V57_RS23350 4973825..4974715 - 891 WP_165169929.1 hypothetical protein -
G5V57_RS23355 4975027..4975581 - 555 WP_165169930.1 hypothetical protein -
G5V57_RS23360 4975608..4976360 - 753 WP_165169931.1 inorganic diphosphatase -
G5V57_RS23365 4976504..4976977 - 474 WP_165169932.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 81 a.a.        Molecular weight: 8880.99 Da        Isoelectric Point: 11.9541

>T151092 WP_165169927.1 NZ_CP049258:4972486-4972728 [Nordella sp. HKS 07]
MPRGDKSSYTGKQKRRAEHIEEGYEKRGVSRKEAAKRAWATVNKESGGGKKSRSGRGKAENRSASRRGGHKVAAKKQARR

Download         Length: 243 bp

>T151092 NZ_CP065232:1139202-1139627 [Thalassospira sp. B30-1]
ATGATTCTGCTGGATACAAACGTTATATCGGAGCAGTTTCGAGCCGTACCCGATGAAACGGTGATTGACTGGTTGAATCG
TCAGCCGCTGGAAACGCTTTATCTGGCATCCATGACCGTGGCCGAACTGCGGGCCGGTGTTGCCCTGATGCCCGCAGGTA
AGCGCCGGACAGTGCTCGGTGACAGCATCGAACACCAGGTGTTGCCGGTATTTGTGGGCCGGGTGTTGCCGTTTGATATG
GCTTGCACACGCGCCTATGCCGATGTGCTGGCAGCCGCCCGCAAGGCCGGTAGCGGCATCGAGGCCGCTGATGCCGTCAT
AGCGGCGATTGCCCTGGAGAGCGGTTTCAGCGTGGCAACAAGGGACGTAAGCCCGTTTCTGGCGGCCGGCGTGAACGTCA
TCAACCCTTGGGAAGATCAAGAGTAA

Antitoxin


Download         Length: 329 a.a.        Molecular weight: 35514.63 Da        Isoelectric Point: 9.1641

>AT151092 WP_165169926.1 NZ_CP049258:4971487-4972473 [Nordella sp. HKS 07]
MAPRRPTRKASSKTAVAAGRRIQSAVDRRDRKRSPKKSSSKPMQSGKRAYPKAFPAQHLTKPGVEDDLSYPPLFQAPGYQ
GSEKLKDMVALITGGDSGIGRAIAVLYAREGADIAIAYLNEHDDAEITKAAVEREGSRCLLLPGDVRMAGFCNKAVEETI
RTFGKLDILVNNAAFQEHEYDIEDLSDEHFDHTLKTNLYGYFYMARAAVPHLKPGGSIVMTGSVTGIMGSKHLLDYSMTK
GGIHAFTRSLAGHLIERGIRVNAVAPGPVWTPLNPADKPAKDVKDFGADTPMKRAAQPEEIAPAFVFLAAPCCSSYITGE
VLPIVGGY

Download         Length: 987 bp

>AT151092 NZ_CP065232:1138957-1139205 [Thalassospira sp. B30-1]
ATGAGAGCAGTAACGATCAGGAATGTACCGGAAGAGGTGCATCGTGCCATCCGGGTTAGGGCAGCGCAGAATGGCCGTAC
CTTGCAAGCCGAGATGTGCGAAATATTGGCTACCGCTGTAAAACCGGAAGGTCGGGTAAAGCTGGGTGACTTATTGGCAG
GTATCGGGCGCAAGGTGAAATTGACCGACGAAGAAATGACGGTTTTTGACCGTGACCATTCACCCGCCCGCGCAGCGAGT
TTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References