Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 3572836..3573405 Replicon chromosome
Accession NZ_CP049258
Organism Nordella sp. HKS 07

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag G5V57_RS16795 Protein ID WP_165168743.1
Coordinates 3573157..3573405 (+) Length 83 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag G5V57_RS16790 Protein ID WP_165174156.1
Coordinates 3572836..3573132 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G5V57_RS16760 3568101..3568802 - 702 WP_165168737.1 hypothetical protein -
G5V57_RS16765 3568799..3569197 - 399 WP_165168738.1 phage holin family protein -
G5V57_RS16770 3569221..3569742 - 522 WP_165168739.1 hypothetical protein -
G5V57_RS16775 3569729..3570703 - 975 WP_165168740.1 hypothetical protein -
G5V57_RS16780 3571000..3571500 - 501 WP_165168741.1 ferritin-like domain-containing protein -
G5V57_RS16785 3571796..3572491 + 696 WP_165168742.1 alpha/beta hydrolase -
G5V57_RS16790 3572836..3573132 + 297 WP_165174156.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
G5V57_RS16795 3573157..3573405 + 249 WP_165168743.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G5V57_RS16800 3573753..3574355 - 603 WP_165168744.1 hypothetical protein -
G5V57_RS16805 3574462..3575580 - 1119 WP_165168745.1 serine hydrolase -
G5V57_RS16810 3575594..3576721 - 1128 WP_206530277.1 ATP-binding cassette domain-containing protein -
G5V57_RS16815 3576764..3577906 - 1143 WP_165168747.1 extracellular solute-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-77)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-59)


Sequences

Toxin        


Download         Length: 83 a.a.        Molecular weight: 9273.56 Da        Isoelectric Point: 6.4629

>T151091 WP_165168743.1 NZ_CP049258:3573157-3573405 [Nordella sp. HKS 07]
MLAIVDYISDENPDAAQRPKDEIEASASKLPEHPKLYRSGRIAGTREMVVRPNYLVIYTESTRAVTILRVLHAAQQWPPA
QE

Download         Length: 249 bp

>T151091 NZ_CP065230:3774393-3775049 [Halomonas sp. A40-4]
GTGGCGACCGACCTCTCTCGCAGCCTGAACTCTCGGAAGGCGCTGATCTTCAGGATCACGCATCGTGACAACCTGCCGTG
GCTACTGGCGCATGGCCTCTATTGCCGTTCAGCAGCGGAGCAAGACCCTGGCTTTGTCACCATTGGGAATCGCGACCTGA
TAGGGCGCCGGGCAACACGAGACGTCCCGACCCCTCCGGGTGGCACTCTCAGCGACTATATCCCCTTCTACTTCACGCCA
GCTTCGCCCATGTTGCTCAACATCGTGACCGGCCGCGGCGTGCCCATTCAGCGCAAGGAAGACATCCTGGTGCTGGTCTG
CTCACTGCCACGCTTGCAGGAGATAGGTTCGGCCTTTGTCTTCACCGACCGCCACGCCTACCTGCCCATGGCCCGCTTTA
GCAGCCAGCTGGTGAATCTGGAAGAGTTTGTGCCATGGCCGCTGCTGCAGGCCCAGGACTTCAGTCGGGACAGGGAGGAC
CCGGAGAAGACCGAGCGTTATCAGGCCGAGGCTCTGGCTCATCATCATCTGCCGGCCTCTGCACTGCTTGGCATTGGCAC
GTATACTGACGAGGTGCGAGTCGCCGTCAGAGCACAGGTAGCGGCACACCAGCTTTCGCTGAAGGTGGTTACACGACCCA
ACTGGTTCTTCCAATGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10795.36 Da        Isoelectric Point: 8.6575

>AT151091 WP_165174156.1 NZ_CP049258:3572836-3573132 [Nordella sp. HKS 07]
MAQTSMLHVRVDDKLKAAAAEKLADVGLTVSDAVRILLTRIAKEGGLPAGLTTDPEAYDAWFRAKVQEALDDTRPSVPHR
QVMDEAQALIDRKRRARS

Download         Length: 297 bp

>AT151091 NZ_CP065230:3775046-3776140 [Halomonas sp. A40-4]
ATGATTGAGTATACCCGTGGCAATCTCCTCGAGGCCGATGTCGAGGCACTAGTCAACACCGTCAACACCGTCGGCGTGAT
GGGCAAGGGCATTGCCCTGATGTTCAAGGAGGCGTTCCCCGAGAACTTCGCCGCCTACGAAGCCGCCTGCAAGCATCAGC
AGGTGGTGACCGGCCGCATGTTCGTCACCGAGCGGGATGCCCTGTTGGGGCCGCGCTGGATCATCAACTTCCCGACCAAG
CAGCATTGGCGCGCCAAGACGCGAGTGGAATGGATCGAGTCCGGTCTGGAAGATCTCAAGCAGGTAATCCGCGAAAAGGG
CATTCGCTCCATCGCTTTGCCACCGCTGGGCTGCGGCAACGGGGGGCTCGATTGGGCCATGGTGCGCCCGCGAATCGAGG
CCGCCTTAGCCGAGCTGGATAACGTCCGGGTGCTGGTTTTCGAGCCCACCGTCGAGTATCAAAACGTCGCCAAGCGTAGC
GGCGTGGAGAGGCTTACCCCCGCACGCGCCATGATTGCCGAACTGGTGCGCCGCTATTGGGTGTTAGGCATCGAGTGCTC
ACTGCTGGAGGTCCAGAAACTAGCCTGGCTGATGGAGCAGCGCATCATTGCTCACGGCCTTGAGAACCCACTCAAGCTCG
AATTTCAGCCTCATCGATACGGTCCCTACTCCGACAGGCTGCGCCATCTGCTCAATGGCCTGGACGGCAGCTACCTGCAT
AGCGAGAGACGCATTAACGATGCCACTCCTGAGGAAGTCGTGTGGTTCGATGAATCGCGACGGGATCGGTTGCATGTCTA
CCTGCGCAGCGCCGAAGCACGCCCCTACGTCGGTGTAGTTGAAGAAGTCGATGCACTGATCGACGGCTTCCAGTCACCGC
TGGGAATGGAGGTGTTGGCGACGCTGGACTGGCTCATCAGCCAGGAGTATGTCGAACCGACCGTCGAAGCCATCAAGGAG
GGCCTGCGATATTGGCCCGATGACATTGCCGGTCAGCGCAAGCTGCGGCTGTTCTCGGATCGCCTCATTGCGCTGGCATT
GGAGCGGCTGAGAGAAGGGTCACCGACAACGCAAGCAATATCCACCGCTCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References