Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relE/YoeB-YefM
Location 3497413..3497918 Replicon chromosome
Accession NZ_CP049258
Organism Nordella sp. HKS 07

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag G5V57_RS16420 Protein ID WP_165168677.1
Coordinates 3497664..3497918 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag G5V57_RS16415 Protein ID WP_165168676.1
Coordinates 3497413..3497667 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G5V57_RS16390 3492502..3493401 - 900 WP_165168671.1 DUF937 domain-containing protein -
G5V57_RS16395 3493422..3494075 - 654 WP_165168672.1 DUF937 domain-containing protein -
G5V57_RS16400 3494097..3495443 - 1347 WP_165168673.1 MATE family efflux transporter -
G5V57_RS16405 3495440..3496057 - 618 WP_165168674.1 HAD family phosphatase -
G5V57_RS16410 3496208..3497398 + 1191 WP_165168675.1 aminotransferase class V-fold PLP-dependent enzyme -
G5V57_RS16415 3497413..3497667 + 255 WP_165168676.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
G5V57_RS16420 3497664..3497918 + 255 WP_165168677.1 Txe/YoeB family addiction module toxin Toxin
G5V57_RS16425 3497999..3499411 - 1413 WP_165168678.1 metalloprotease TldD -
G5V57_RS16430 3499429..3500076 - 648 WP_165168679.1 invasion associated locus B family protein -
G5V57_RS16435 3500353..3501240 + 888 WP_165168680.1 cytochrome c oxidase subunit II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10087.52 Da        Isoelectric Point: 9.5575

>T151090 WP_165168677.1 NZ_CP049258:3497664-3497918 [Nordella sp. HKS 07]
VKLIFSEQAWEDYLHWQTQDRKLLERINALIKECSRTPFKGTGKPEPLRGSLSGWWSRRITQEHRLVYRPSEDGLLIAQC
RYHY

Download         Length: 255 bp

>T151090 NZ_CP065230:3547110-3547373 [Halomonas sp. A40-4]
ATGAATAGTCGTTTGTTGTGCTGGACGAATGAAGCTTGGAGTGACTACCTCTATTGGCAAGGGCAGGATAAAAAGACCTT
AAAGCGCATCAATAAACTTATCTCAGATACGCAACGCTCTCCCTTCGAGGGCATTGGAAAGCCAGAACCCCTCAGGGAAA
ACCTCTCAGGCTTATGGTCGCGACGCATCGACGACACACATCGCTTGGTTTATGCCGTTGATGCATCCACTCTCACTATT
ATTGCCTGCCGCTACCATTACTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9405.61 Da        Isoelectric Point: 5.1767

>AT151090 WP_165168676.1 NZ_CP049258:3497413-3497667 [Nordella sp. HKS 07]
MKTKSYSELRQNLAATLDSVTEDHEPVIITRDRGKPAAVLISLEDFASYEESRYLLQSPRNADRLLKAVAELEAGKGTER
KLAE

Download         Length: 255 bp

>AT151090 NZ_CP065230:3546863-3547117 [Halomonas sp. A40-4]
ATGCGTGTTATATCGTTTACCGAAGCGCGGAACGGCCTGAAAAGCTTACTGGACGGTGTCGTCAATGATGCCGATACCAC
GATTATTACCCGCCGCGACGCAGAAGATGCAGTGGTCATGTCACTCGACTACTACAACAGCCTTATGGAAACCGTTTACT
TGATGCGCTCACCCGCTAACGCGGAGCGCTTAAATAAGTCCATTGCTCAGTACCGTGCGGGGCAGGCGCAATCAAGGGAA
CTAATAGATGAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References