Detailed information of TA system TA151089

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-RHH
• Location: 115551..116077
• Replicon: chromosome
• Accession: NZ_CP049258
• Organism: Nordella sp. HKS 07

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: G5V57_RS00510
• Protein ID: WP_165165638.1
• Coordinates: 115787..116077 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: G5V57_RS00505
• Protein ID: WP_165165636.1
• Coordinates: 115551..115790 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G5V57_RS00465	111040..111393	-	354	WP_165165621.1	GFA family protein	-
G5V57_RS00470	111420..112373	-	954	WP_165165623.1	LysR family transcriptional regulator	-
G5V57_RS00475	112481..113128	+	648	WP_165165625.1	FMN-dependent NADH-azoreductase	-
G5V57_RS00480	113235..113855	+	621	WP_165165627.1	UdgX family uracil-DNA binding protein	-
G5V57_RS00485	113857..114276	-	420	WP_165165629.1	secondary thiamine-phosphate synthase enzyme YjbQ	-
G5V57_RS00490	114337..114798	+	462	WP_165165631.1	host attachment family protein	-
G5V57_RS00495	114860..115048	-	189	WP_165165633.1	hypothetical protein	-
G5V57_RS00500	115109..115402	-	294	WP_165165634.1	hypothetical protein	-
G5V57_RS00505	115551..115790	+	240	WP_165165636.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
G5V57_RS00510	115787..116077	+	291	WP_165165638.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
G5V57_RS00515	116102..116932	+	831	WP_165165640.1	hypothetical protein	-
G5V57_RS00520	117263..119314	-	2052	WP_165173690.1	RNA polymerase sigma factor RpoD	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Antitoxin ParD (3-71)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11020.64 Da
• Isoelectric Point: 9.5582

>T151089 WP_165165638.1 NZ_CP049258:115787-116077 [Nordella sp. HKS 07]
MIALRFTPRARADFDGIWDYTAENWNLDQAEAYLRAINQALNLLRANPRLGRSASDIGQGLFKFPVASHIIYYRFASSTL
IVVRLLHKSMDVEQHL

Nucleotide

• Length: 291 bp

>T151089 NZ_CP065230:3546863-3547117 [Halomonas sp. A40-4]
ATGCGTGTTATATCGTTTACCGAAGCGCGGAACGGCCTGAAAAGCTTACTGGACGGTGTCGTCAATGATGCCGATACCAC
GATTATTACCCGCCGCGACGCAGAAGATGCAGTGGTCATGTCACTCGACTACTACAACAGCCTTATGGAAACCGTTTACT
TGATGCGCTCACCCGCTAACGCGGAGCGCTTAAATAAGTCCATTGCTCAGTACCGTGCGGGGCAGGCGCAATCAAGGGAA
CTAATAGATGAATAG

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8872.14 Da
• Isoelectric Point: 9.9470

>AT151089 WP_165165636.1 NZ_CP049258:115551-115790 [Nordella sp. HKS 07]
MKNTSVVLGKQHTAFIKKQVRKGRFGSASEAVRAGLQLLEEQELRMERLRTAINEGDASGEPEPFDIEEFIAEKKKAAR

Nucleotide

• Length: 240 bp

>AT151089 NZ_CP065230:3547110-3547373 [Halomonas sp. A40-4]
ATGAATAGTCGTTTGTTGTGCTGGACGAATGAAGCTTGGAGTGACTACCTCTATTGGCAAGGGCAGGATAAAAAGACCTT
AAAGCGCATCAATAAACTTATCTCAGATACGCAACGCTCTCCCTTCGAGGGCATTGGAAAGCCAGAACCCCTCAGGGAAA
ACCTCTCAGGCTTATGGTCGCGACGCATCGACGACACACATCGCTTGGTTTATGCCGTTGATGCATCCACTCTCACTATT
ATTGCCTGCCGCTACCATTACTAA