Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PhRel-ATphRel/-
Location 865072..866125 Replicon chromosome
Accession NZ_CP049255
Organism Microbacterium endophyticum strain DSM 27099

Toxin (Protein)


Gene name phRel Uniprot ID -
Locus tag G6N83_RS04030 Protein ID WP_165139514.1
Coordinates 865298..866125 (-) Length 276 a.a.

Antitoxin (Protein)


Gene name ATphRel Uniprot ID -
Locus tag G6N83_RS04025 Protein ID WP_165139511.1
Coordinates 865072..865293 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6N83_RS04005 861656..862321 + 666 WP_165139503.1 DUF1028 domain-containing protein -
G6N83_RS04010 862302..862895 - 594 WP_165139505.1 XRE family transcriptional regulator -
G6N83_RS04015 862986..863630 + 645 WP_165143106.1 hypothetical protein -
G6N83_RS04020 863632..864972 - 1341 WP_165139509.1 amidohydrolase family protein -
G6N83_RS04025 865072..865293 - 222 WP_165139511.1 hypothetical protein Antitoxin
G6N83_RS04030 865298..866125 - 828 WP_165139514.1 hypothetical protein Toxin
G6N83_RS04035 866344..866778 - 435 WP_165139516.1 Hsp20/alpha crystallin family protein -
G6N83_RS04040 866912..867706 - 795 WP_165139519.1 class I SAM-dependent methyltransferase -
G6N83_RS04045 867706..868491 - 786 WP_165139522.1 ABC transporter ATP-binding protein -
G6N83_RS04050 868488..869480 - 993 WP_165139525.1 ABC transporter substrate-binding protein -
G6N83_RS04055 869519..870595 - 1077 WP_165139527.1 iron ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(59-165)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 276 a.a.        Molecular weight: 31851.17 Da        Isoelectric Point: 6.7686

>T151087 WP_165139514.1 NZ_CP049255:c866125-865298 [Microbacterium endophyticum]
MEPLPWSKNQLKRLSRHIRDGTTPEQGLPSYGAVMLWYNDLAEHVQFVVSTLDWTPILGERPFEVTSRPKTLDTLRQKLN
RDTDTPLPSVQDVAGVRFEAEMTLDEQDAVVNAITGRFEHKLDDCVRDMRATPHSGYRAVHIWLKLEARVEVQVRTHLQG
DWANMYEVAADLYGRQIRYDALPADPIEKKIVRSLRAVSELRISQIEKDRNEISLLELNLEETPIIVRTRAQYRDVARRV
ETLKARNLRNEQELQNGLEMLRKTFREGQRGSEGV

Download         Length: 828 bp

>T151087 NZ_CP065230:972298-972561 [Halomonas sp. A40-4]
ATGAGCGACTTTGAGTATGATGATGACAAAAGCGTAGCCAATCTGATAAAGCATGGAATTGACTTTCTAGATGCTCAGGC
GCTTTGGAATGATCCTGATTTGCTGGAAATTCAAGCCAAATCTGATGATGAGCCGCGTTTTCTGATGATAGGGCTGATTG
ATGATAAACACTGGTCTGCCGTCATCACCTACCGAAATGAAAAAATTCGACTCATTTCGGTAAGGCGCTCGCGTAAAAGA
GAGGTAGAGCTCTATGAAAGCTAA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8508.32 Da        Isoelectric Point: 6.6426

>AT151087 WP_165139511.1 NZ_CP049255:c865293-865072 [Microbacterium endophyticum]
VAGFVIEYNRLSGERHVHSFAGPDGHREALRYRLQLEQNRADDGWEIVSLNSDSIETVHRTHARYFERDRLSA

Download         Length: 222 bp

>AT151087 NZ_CP065230:972551-972811 [Halomonas sp. A40-4]
ATGAAAGCTAACGACTTTGATCAAAAATTTGACCAGGGTAGCGAAGACATCGTTGACGATCTTGATTTATCCACTGCACA
CCGTGTTAATCAAGATCCGAAGCGTATCAATGTCGACTTCCCCGCTTGGGTGGTTGAGTCCCTGGATCGTGAGGCCGCCC
GTATCGGCGTTACGCGTCAATCTATTATCAAAGTTTGGCTGGTTGAACGGTTGAAAGCCGAAGCGAGTCAAAAGCTTCCG
GATAACACGCAGCCTCACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References