Detailed information of TA system TA151080

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): hicAB/HicA-HicB
• Location: 1747186..1747781
• Replicon: chromosome
• Accession: NZ_CP049241
• Organism: Rhizobium pseudoryzae strain DSM 19479

Toxin (Protein)

• Gene name: hicA
• Uniprot ID: -
• Locus tag: G6N78_RS08430
• Protein ID: WP_165217385.1
• Coordinates: 1747186..1747371 (+)
• Length: 62 a.a.

Antitoxin (Protein)

• Gene name: hicA
• Uniprot ID: -
• Locus tag: G6N78_RS08435
• Protein ID: WP_165217387.1
• Coordinates: 1747383..1747781 (+)
• Length: 133 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G6N78_RS08420	1742857..1744506	-	1650	WP_165217381.1	siroheme synthase CysG	-
G6N78_RS08425	1744478..1747129	-	2652	WP_165217383.1	nitrate reductase	-
G6N78_RS08430	1747186..1747371	+	186	WP_165217385.1	type II toxin-antitoxin system HicA family toxin	Toxin
G6N78_RS08435	1747383..1747781	+	399	WP_165217387.1	type II toxin-antitoxin system HicB family antitoxin	Antitoxin
G6N78_RS08440	1747798..1748130	-	333	WP_165217389.1	nitrite reductase small subunit NirD	-
G6N78_RS08445	1748261..1750711	-	2451	WP_165217391.1	nitrite reductase large subunit NirB	-
G6N78_RS08450	1750717..1751517	-	801	WP_165217392.1	ABC transporter ATP-binding protein	-
G6N78_RS08455	1751529..1752425	-	897	WP_165217394.1	nitrate ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HicA mRNA interferase family (6-59)

Antitoxin

• HicB-like antitoxin of toxin-antitoxin system (4-124)

Sequences

Toxin

Protein

• Length: 62 a.a.
• Molecular weight: 6915.99 Da
• Isoelectric Point: 10.6573

>T151080 WP_165217385.1 NZ_CP049241:1747186-1747371 [Rhizobium pseudoryzae]
MERDSRKIIQSLKDEGFELVAVRGSHHKFRKEGHTVVVPHPKKDLPVGTARAIAKQTGWIE

Nucleotide

• Length: 186 bp

>T151080 NZ_CP049241:1747186-1747371 [Rhizobium pseudoryzae]
ATGGAGCGGGACAGCCGAAAGATCATCCAGAGCCTCAAGGACGAAGGCTTCGAACTGGTGGCGGTGCGAGGTTCGCACCA
CAAGTTCCGCAAGGAGGGGCACACCGTCGTCGTCCCCCATCCGAAGAAGGATTTGCCCGTGGGCACAGCCCGCGCCATTG
CCAAACAGACCGGCTGGATCGAGTAG

Antitoxin

Protein

• Length: 133 a.a.
• Molecular weight: 14349.18 Da
• Isoelectric Point: 4.4089

>AT151080 WP_165217387.1 NZ_CP049241:1747383-1747781 [Rhizobium pseudoryzae]
MRHYIALVHRDADSAFGVSFPDVPGVFSAADAEEDIIANAIEALRLWAEDETLPQPSAIERVIERDDIRAELATGAFLVR
VPLIEDDSRVVRANVTFEAGTLKAIDAEAARRGLTRSAFLASCARKEIEAVG

Nucleotide

• Length: 399 bp

>AT151080 NZ_CP049241:1747383-1747781 [Rhizobium pseudoryzae]
ATGCGCCATTACATCGCCCTCGTGCACAGGGATGCCGACAGTGCCTTCGGCGTCAGTTTTCCGGATGTGCCAGGCGTCTT
TTCGGCGGCGGATGCGGAGGAAGACATCATCGCCAATGCCATCGAGGCGTTGCGGCTCTGGGCGGAGGATGAAACGCTGC
CGCAACCCTCCGCCATCGAACGCGTCATCGAACGTGACGATATCCGGGCGGAACTTGCCACTGGTGCCTTCCTGGTGCGG
GTTCCCCTGATCGAGGATGACAGCCGTGTCGTGCGTGCCAACGTGACCTTTGAAGCCGGGACGCTGAAGGCCATTGATGC
GGAAGCCGCCCGTCGCGGGCTGACGCGGTCGGCCTTTCTCGCCAGCTGTGCGCGCAAGGAAATCGAAGCGGTCGGATAG