Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 294299..294842 Replicon chromosome
Accession NZ_CP049241
Organism Rhizobium pseudoryzae strain DSM 19479

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag G6N78_RS01625 Protein ID WP_165215040.1
Coordinates 294299..294598 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag G6N78_RS01630 Protein ID WP_165215042.1
Coordinates 294591..294842 (-) Length 84 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6N78_RS01605 289802..291067 + 1266 WP_165215030.1 phosphoribosylamine--glycine ligase -
G6N78_RS01610 291190..291681 + 492 WP_165215032.1 hypothetical protein -
G6N78_RS01615 291919..293748 + 1830 WP_165215035.1 methyl-accepting chemotaxis protein -
G6N78_RS01620 293806..294294 - 489 WP_165215037.1 DUF523 domain-containing protein -
G6N78_RS01625 294299..294598 - 300 WP_165215040.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6N78_RS01630 294591..294842 - 252 WP_165215042.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
G6N78_RS01635 294945..297515 - 2571 WP_165215045.1 glycine--tRNA ligase subunit beta -
G6N78_RS01640 297677..299620 - 1944 WP_165215047.1 DUF2207 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-92)

Antitoxin

(1-80)


Sequences


Toxin        


Download         Length: 100 a.a.        Molecular weight: 11565.06 Da        Isoelectric Point: 6.4872

>T151077 WP_165215040.1 NZ_CP049241:c294598-294299 [Rhizobium pseudoryzae]
VVEVRLRPSAQRDFVDIGDQTRDRWSEAQAERYLKQILEMIAEIGRHPFAGIDVPSIRSDYRRRRAGSHLIFYAILDDGT
VEVVRILHERADVPRHLDE

Download         Length: 300 bp

>T151077 NZ_CP065211:216353-216619 [Enterococcus lactis]
ATGAGTAACTATACAGTCGCAATCAAAAACTCTGCGAAAGTGGATTTAAGAAAAATCAAGCAATCGAATTTAAAGAAACA
ATTTGAAGAAGTGATTCAGACATTGAAGGAAGATCCATATATGCCCACGCAGTCTTTTGAAAAGCTGAGACCTACACATG
AAGGCAGATACTCACGCAGGCTGAATAGACAGCATCGAGTGGTTTACAAAGTTGATGAGGAAAATAAAGTTGTGGAAATT
TATTCTGCCTGGACACATTATGAGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9585.75 Da        Isoelectric Point: 4.4128

>AT151077 WP_165215042.1 NZ_CP049241:c294842-294591 [Rhizobium pseudoryzae]
MNKPFQVTLVEPLDRFVEEQVESGRFSSPQDVVEAGLRLLEEDQRKLEWLRNALIEGENSGPSVPFDPEELMRSVRARWT
SRG

Download         Length: 252 bp

>AT151077 NZ_CP065211:216090-216353 [Enterococcus lactis]
ATGGCTAATACAACGATGAATCCTAGCACTGCTCGTAAAAATTTTTATCAGTTATTGAAAGAGGTAAATGAAAATCATAC
TGAAATCGAGATTATTAGTGATCGTAGTGGAAACAATGCTGTATTGATTGGGCTGGAAGACTGGAGAGCGATTCAAGAAA
CCCTTTTTCTTGAGCAAACAGGTACTTTAGATAAAGTACGAGACCGCGAAAAAGACGACAGTGGCTTTACGAATATCGAT
GATATTGATTGGGAAGCTCTTTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References