Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/HTH_26(antitoxin) |
Location | 148507..149109 | Replicon | chromosome |
Accession | NZ_CP049241 | ||
Organism | Rhizobium pseudoryzae strain DSM 19479 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | G6N78_RS00905 | Protein ID | WP_165214655.1 |
Coordinates | 148864..149109 (-) | Length | 82 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | G6N78_RS00900 | Protein ID | WP_165214652.1 |
Coordinates | 148507..148857 (-) | Length | 117 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
G6N78_RS00880 | 143551..145356 | - | 1806 | WP_165214641.1 | GGDEF domain-containing protein | - |
G6N78_RS00885 | 145465..146019 | - | 555 | WP_165214644.1 | HdeD family acid-resistance protein | - |
G6N78_RS00890 | 146177..146788 | + | 612 | WP_165214647.1 | transcriptional regulator BetI | - |
G6N78_RS00895 | 146785..148248 | + | 1464 | WP_165214650.1 | betaine-aldehyde dehydrogenase | - |
G6N78_RS00900 | 148507..148857 | - | 351 | WP_165214652.1 | helix-turn-helix transcriptional regulator | Antitoxin |
G6N78_RS00905 | 148864..149109 | - | 246 | WP_165214655.1 | cytotoxic translational repressor of toxin-antitoxin stability system | Toxin |
G6N78_RS00910 | 149205..150860 | + | 1656 | WP_165214677.1 | choline dehydrogenase | - |
G6N78_RS00915 | 150915..151136 | - | 222 | WP_165214679.1 | ribbon-helix-helix domain-containing protein | - |
G6N78_RS00920 | 151249..151842 | + | 594 | WP_165214681.1 | RNA polymerase sigma factor | - |
G6N78_RS00925 | 151835..152149 | + | 315 | WP_165214683.1 | hypothetical protein | - |
G6N78_RS00930 | 152146..152595 | + | 450 | WP_165214685.1 | periplasmic heavy metal sensor | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 82 a.a. Molecular weight: 9122.83 Da Isoelectric Point: 11.0727
>T151075 WP_165214655.1 NZ_CP049241:c149109-148864 [Rhizobium pseudoryzae]
MKEVVVSQRADKALQNMQPKRRLAILAKVKAYARGERVDIKKLKGLELWRIRVGNDRVIIDDQGGIVLVVPAGPRGSIYK
E
MKEVVVSQRADKALQNMQPKRRLAILAKVKAYARGERVDIKKLKGLELWRIRVGNDRVIIDDQGGIVLVVPAGPRGSIYK
E
Download Length: 246 bp
>T151075 NZ_CP065210:190137-190403 [Enterococcus faecium]
ATGAGTAACTATACAGTCGCAATCAAAAACTCTGCGAAAGTGGATTTAAGAAAAATCAAGCAATCGAATTTAAAGAAACA
ATTTGAAGAAGTGATTCAGACATTGAAGGAAGATCCATATATGCCCACGCAGTCTTTTGAAAAGCTGAGACCTACACATG
AAGGCAGATACTCACGCAGGCTGAATAGACAGCATCGAGTGGTTTACAAAGTTGATGAGGAAAATAAAGTTGTGGAAATT
TATTCTGCCTGGACACATTATGAGTGA
ATGAGTAACTATACAGTCGCAATCAAAAACTCTGCGAAAGTGGATTTAAGAAAAATCAAGCAATCGAATTTAAAGAAACA
ATTTGAAGAAGTGATTCAGACATTGAAGGAAGATCCATATATGCCCACGCAGTCTTTTGAAAAGCTGAGACCTACACATG
AAGGCAGATACTCACGCAGGCTGAATAGACAGCATCGAGTGGTTTACAAAGTTGATGAGGAAAATAAAGTTGTGGAAATT
TATTCTGCCTGGACACATTATGAGTGA
Antitoxin
Download Length: 117 a.a. Molecular weight: 12693.47 Da Isoelectric Point: 4.4393
>AT151075 WP_165214652.1 NZ_CP049241:c148857-148507 [Rhizobium pseudoryzae]
MGRVQKIEIEGKSYVLLSEEDYEDLVDGLEASAVLAKVADGQEVWPLEIVEARANGENPVRVFRTYRKMSVSELAAAAAI
SQPYLSEIESGKKTGSVDVLKRIAAALKVDLDDIVR
MGRVQKIEIEGKSYVLLSEEDYEDLVDGLEASAVLAKVADGQEVWPLEIVEARANGENPVRVFRTYRKMSVSELAAAAAI
SQPYLSEIESGKKTGSVDVLKRIAAALKVDLDDIVR
Download Length: 351 bp
>AT151075 NZ_CP065210:189874-190137 [Enterococcus faecium]
ATGGCTAATACAACGATGAATCCTAGCACTGCTCGTAAAAATTTTTATCAGTTATTGAAAGAGGTAAATGAAAATCATAC
TGAAATCGAGATTATTAGTGATCGTAGTGGAAACAATGCTGTATTGATTGGGCTAGAAGACTGGAGAGCGATTCAAGAAA
CCCTTTTTCTTGAGCAAACAGGTACTTTAGATAAAGTACGAGACCGCGAAAAAGACGACAGTGGCTTTACGAATATCGAT
GATATTGATTGGGAAGCTCTTTGA
ATGGCTAATACAACGATGAATCCTAGCACTGCTCGTAAAAATTTTTATCAGTTATTGAAAGAGGTAAATGAAAATCATAC
TGAAATCGAGATTATTAGTGATCGTAGTGGAAACAATGCTGTATTGATTGGGCTAGAAGACTGGAGAGCGATTCAAGAAA
CCCTTTTTCTTGAGCAAACAGGTACTTTAGATAAAGTACGAGACCGCGAAAAAGACGACAGTGGCTTTACGAATATCGAT
GATATTGATTGGGAAGCTCTTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|