Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 76414..77000 Replicon chromosome
Accession NZ_CP049241
Organism Rhizobium pseudoryzae strain DSM 19479

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag G6N78_RS00445 Protein ID WP_165221076.1
Coordinates 76414..76704 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag G6N78_RS00450 Protein ID WP_165214407.1
Coordinates 76701..77000 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6N78_RS00420 72380..72775 - 396 WP_165214394.1 DUF930 domain-containing protein -
G6N78_RS00425 72909..73181 + 273 WP_165214403.1 hypothetical protein -
G6N78_RS00430 73389..75494 + 2106 WP_165214405.1 S9 family peptidase -
G6N78_RS00435 75600..76046 - 447 WP_165214231.1 hypothetical protein -
G6N78_RS25685 76181..76393 - 213 WP_206531587.1 hypothetical protein -
G6N78_RS00445 76414..76704 + 291 WP_165221076.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6N78_RS00450 76701..77000 + 300 WP_165214407.1 putative addiction module antidote protein Antitoxin
G6N78_RS00455 77130..78554 - 1425 WP_206531588.1 PepSY domain-containing protein -
G6N78_RS00460 78719..79132 - 414 WP_165214409.1 hypothetical protein -
G6N78_RS00465 79289..80548 + 1260 WP_165214411.1 DUF2254 domain-containing protein -
G6N78_RS00470 80755..81009 + 255 WP_165214413.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-89)

Antitoxin

Uncharacterized protein HI1420

(15-93)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10989.84 Da        Isoelectric Point: 10.6020

>T151074 WP_165221076.1 NZ_CP049241:76414-76704 [Rhizobium pseudoryzae]
MIEVRQHPDFVRWLRSLRDRAAQVRIAMRLVRLEAGLMGDAKFFDGIGELRIDYGPGYRVYFVKRGTRLIILLCGGDKSS
QARDIAQAKRLAEDVP

Download         Length: 291 bp

>T151074 NZ_CP065209:c1411711-1411220 [Bifidobacterium longum subsp. longum]
ATGAGGCAGTCAAAGCAGGTGTCGATCTTGTGCGACACCAATATCCTTATTTATTACATGCTCTGTACGCCTCGGTTCAT
CAAGGATGTCATGAAACTGTTCGAGCGATGCGTCGAGCGGGAGGTAAAGCTGTCCTGTGCGTCACTGTCGCTGAAGGACG
TGTTCTACATCACCCCGGAACGATTCAAAGAACGATTCATGAATGACGAATCCATGGTCGTTGCGACCACCGCCAAGCTG
ATATTGCCGGAGGTGGCATGGTCGGGAATCAGCAAACTCAAGGAGCTCATGACAATCGTGCCGATTGGCGCGGAGGAATG
TGAATTGGCGCAGTCGTTGCGGCACGCGCATAACGATTTCGAGGATGACCTTATTATCGCCGCCGCACAACAATCCGGGG
CCACCTATGTGGTGACGTATGACAAAAAACTAGCCAAGCATTTTCCCGAATATTGCAAAACGCCGGCTGAAATCGTGGCG
GCGCTGGCATAG

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10360.88 Da        Isoelectric Point: 4.4488

>AT151074 WP_165214407.1 NZ_CP049241:76701-77000 [Rhizobium pseudoryzae]
MTVEPIPFEASEFFETVDSQALLLSDALETGDCAYIAHAFGVIAKARGMTGIAREAGVTREALYKALSEKGDPKLSTLLG
VAKALGLKFTVVPASDAAE

Download         Length: 300 bp

>AT151074 NZ_CP065209:c1412100-1411708 [Bifidobacterium longum subsp. longum]
ATGACCATGGTCCAAATGAACGTTCGCATTGATGCGAAACTGAAGAACGAGGTCGAAGAAGTCCTCAAGGGCAAAGGCGT
ATCGGTGAGTGACGTAATCCGGTCGCTGTGGTTGTACATCGCCGACCGCAAGGAAGTGCCGGCCTTGGAAACGACCGCCG
AAGAGCAAGCCCGCGAGGAGGAAAAGCAGCGCAAGCTGAAACTGATTCGAGAAGGTGCCGGATACGTACACAAGGAACTG
GTCAAGGCCGGACTGATCTCAGAAGACACCGACCTCATGGAAGGCCTTACCTACAAGCAGTTCCGCGATGAGATAGCTGA
CGAACGGCTGAAGGAATACAGGCATCAGTCGGACTATGCGCGTTATTTGGAGAAGGAGCGGAGTCTGTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References