Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 666079..666647 Replicon chromosome
Accession NZ_CP049231
Organism Lactobacillus iners strain C0254C1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag G6Z81_RS03445 Protein ID WP_164799433.1
Coordinates 666369..666647 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag G6Z81_RS03440 Protein ID WP_006736912.1
Coordinates 666079..666363 (+) Length 95 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6Z81_RS03415 661903..663312 - 1410 WP_164799431.1 RsmF rRNA methyltransferase first C-terminal domain-containing protein -
G6Z81_RS03420 663312..664292 - 981 WP_006738135.1 hypothetical protein -
G6Z81_RS03425 664279..665025 - 747 WP_164799432.1 SAM-dependent methyltransferase -
G6Z81_RS03430 665113..665715 + 603 WP_006729930.1 signal peptidase I -
G6Z81_RS03435 665731..665916 + 186 WP_006732263.1 hypothetical protein -
G6Z81_RS03440 666079..666363 + 285 WP_006736912.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
G6Z81_RS03445 666369..666647 + 279 WP_164799433.1 type II toxin-antitoxin system YafQ family toxin Toxin
G6Z81_RS03450 667083..667796 - 714 WP_006738361.1 M48 family metallopeptidase -
G6Z81_RS03455 668066..668350 + 285 WP_102215227.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
G6Z81_RS03460 668651..669541 - 891 WP_006736250.1 GIY-YIG nuclease family protein -
G6Z81_RS06595 669912..670124 + 213 WP_035511922.1 hypothetical protein -
G6Z81_RS03470 670387..671076 - 690 WP_006736915.1 ABC transporter ATP-binding protein -
G6Z81_RS03475 671069..671443 - 375 WP_006731653.1 GntR family transcriptional regulator -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-90)

Antitoxin

(5-69)


Sequences


Toxin        


Download         Length: 93 a.a.        Molecular weight: 10835.61 Da        Isoelectric Point: 9.0049

>T151065 WP_164799433.1 NZ_CP049231:666369-666647 [Lactobacillus iners]
MLQLKTTSKFRKDYRRIKKRGLDIYLLKEVLDKLCARETLDLKYKDHALSGSYQGFRECHIQPDWLLIYAISEDEIILVA
SRTGSHADLFNM

Download         Length: 279 bp

>T151065 NZ_CP065199:c2434022-2433915 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10516.02 Da        Isoelectric Point: 5.1231

>AT151065 WP_006736912.1 NZ_CP049231:666079-666363 [Lactobacillus iners]
MAKTANINVRIEPEVKQQAEDLFGSFGISVTDAINIFLRTSIMEGGFPFKIRKPRFNAETLAAMQEARDIMSGKIQAKSY
KTTDEFIQALNAED

Download         Length: 285 bp

>AT151065 NZ_CP065199:2433838-2433898 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References