151060

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 1040153..1040633 Replicon chromosome
Accession NZ_CP049213
Organism Agrobacterium rhizogenes strain CA75/95

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag G6M87_RS05035 Protein ID WP_007699858.1
Coordinates 1040153..1040422 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag G6M87_RS05040 Protein ID WP_007699854.1
Coordinates 1040406..1040633 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6M87_RS05000 (G6M87_05010) 1035288..1036313 - 1026 WP_007699878.1 NAD(P)-dependent alcohol dehydrogenase -
G6M87_RS05005 (G6M87_05015) 1036424..1037326 + 903 WP_007699876.1 LysR family transcriptional regulator -
G6M87_RS05010 (G6M87_05020) 1037316..1037648 - 333 WP_007699873.1 YciI family protein -
G6M87_RS05015 (G6M87_05025) 1037712..1038617 + 906 WP_234905323.1 LysR family transcriptional regulator -
G6M87_RS05020 (G6M87_05030) 1038669..1039037 - 369 WP_007699866.1 DUF305 domain-containing protein -
G6M87_RS05025 (G6M87_05035) 1039118..1039498 - 381 WP_007699863.1 hypothetical protein -
G6M87_RS05030 (G6M87_05040) 1039567..1040121 - 555 WP_178132482.1 2'-5' RNA ligase family protein -
G6M87_RS05035 (G6M87_05045) 1040153..1040422 - 270 WP_007699858.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6M87_RS05040 (G6M87_05050) 1040406..1040633 - 228 WP_007699854.1 DUF6290 family protein Antitoxin
G6M87_RS05045 (G6M87_05055) 1040810..1042324 + 1515 WP_007699851.1 histidine--tRNA ligase -
G6M87_RS05050 (G6M87_05060) 1042325..1043443 + 1119 WP_007699848.1 ATP phosphoribosyltransferase regulatory subunit -
G6M87_RS05055 (G6M87_05065) 1043443..1044156 + 714 WP_007699845.1 ATP phosphoribosyltransferase -
G6M87_RS05060 (G6M87_05070) 1044248..1044637 - 390 WP_007699842.1 type II toxin-antitoxin system VapC family toxin -
G6M87_RS05065 (G6M87_05075) 1044624..1044899 - 276 WP_007699840.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
G6M87_RS05070 (G6M87_05080) 1045044..1045487 - 444 WP_007699838.1 DoxX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Relaxosome protein TraY

(7-50)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10582.11 Da        Isoelectric Point: 10.3321

>T151060 WP_007699858.1 NZ_CP049213:c1040422-1040153 [Agrobacterium rhizogenes]
VAWTIEYARSARKFVEKLDPKTRSRIRTFLEERLSSLHDPRQVGDALQGARLGNYWRYRVGDYRIICDLQDSRLVVLVVE
IGNRRDVYR

Download         Length: 270 bp

>T151060 NZ_CP065199:c1906327-1906175 [Staphylococcus aureus]
ATGTCTAAAGACAAAGATCCAAAATTAAATTATCATGAAGAAGAAAACAGTATGGTAACTGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAAATGGAACAAATCTCTGATCAAAATGATCAAGAAAAAAATTCTGAAGAAGACAGTCAGTAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8806.75 Da        Isoelectric Point: 4.3135

>AT151060 WP_007699854.1 NZ_CP049213:c1040633-1040406 [Agrobacterium rhizogenes]
MSKQTAIRLPDETYERLQALAERTGRTATYYIRQAIEAHLDDLEDVYLAERAMERIKNGEDEIISSEEFWRGLDN

Download         Length: 228 bp

>AT151060 NZ_CP065199:c1906951-1906352 [Staphylococcus aureus]
ATGGCAATGAACTTTAAAGTCTTTGACAATAGTCAACTTGTAGCAGAATATGCTGCTGATATTATTAGAAAGCAATTTAA
CAATAATCCTACTACAATTGCAGGTTTTCATTTAGATACAGATCAAGCGCCAGTTCTAGATGAATTAAAGAAAAATGTTG
AAAAATATGCTGTTGATTTTAGCCAAATAAATATTTTAGATTATGACGATAAAAAATCATATTTCGAAGCGTTAGGTGTA
CCAGCAGGTCAAGTTTATCCAATTGCTTATGAAAAAGATGCAATCGAATTAATCGCTGATAAGATTAAAACTAAAGAAAA
TAAAGGGAAATTAACATTACAAGTTGTTTCTATCGATGAGCAAGGTAAGTTAAATGTTAGTATTCGTCAAGGACTAATGG
AAGCAAGAGAAATTTTCTTAGTAGTGACAGGTGCTAATAAACGAGATGTAGTTGAAAAATTATATCAAGAAAATGGTAAA
ACAAGCTTCGAACCAGCCGATTTAAAAGCACATAGAATGGTAAATGTTATTCTTGATAAAGAAGCGGCTGCAGGTTTACC
TGAAGATGTTAAAGCTTACTTTACGTCACGCTTTGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References