Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-VagC |
Location | 659091..659725 | Replicon | chromosome |
Accession | NZ_CP049213 | ||
Organism | Agrobacterium rhizogenes strain CA75/95 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | G6M87_RS03145 | Protein ID | WP_007702741.1 |
Coordinates | 659091..659486 (-) | Length | 132 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | B9J7R9 |
Locus tag | G6M87_RS03150 | Protein ID | WP_007702738.1 |
Coordinates | 659483..659725 (-) | Length | 81 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
G6M87_RS03115 (G6M87_03125) | 654105..654560 | + | 456 | WP_007702750.1 | ester cyclase | - |
G6M87_RS03120 (G6M87_03130) | 654623..655387 | - | 765 | WP_007702749.1 | SDR family oxidoreductase | - |
G6M87_RS03125 (G6M87_03135) | 655507..656412 | + | 906 | WP_007702748.1 | LysR family transcriptional regulator | - |
G6M87_RS03130 (G6M87_03140) | 656413..657288 | - | 876 | WP_007702747.1 | LysR family transcriptional regulator | - |
G6M87_RS03135 (G6M87_03145) | 657386..658669 | + | 1284 | WP_007702745.1 | MFS transporter | - |
G6M87_RS03140 (G6M87_03150) | 658693..659094 | + | 402 | WP_007702743.1 | VOC family protein | - |
G6M87_RS03145 (G6M87_03155) | 659091..659486 | - | 396 | WP_007702741.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
G6M87_RS03150 (G6M87_03160) | 659483..659725 | - | 243 | WP_007702738.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
G6M87_RS03155 (G6M87_03165) | 659794..660471 | - | 678 | WP_007702735.1 | spermidine synthase | - |
G6M87_RS03160 (G6M87_03170) | 660542..662203 | - | 1662 | WP_007702732.1 | urocanate hydratase | - |
G6M87_RS03165 (G6M87_03175) | 662227..662556 | - | 330 | WP_007702728.1 | TfoX/Sxy family protein | - |
G6M87_RS03170 (G6M87_03180) | 662572..663672 | - | 1101 | WP_007702725.1 | DUF917 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 132 a.a. Molecular weight: 14661.85 Da Isoelectric Point: 7.4004
>T151059 WP_007702741.1 NZ_CP049213:c659486-659091 [Agrobacterium rhizogenes]
VKYLLDSNAVIALMKGHSGFVAEIRKHKPQDFAIPAIVAHELFYGAYKGQRVADNLARVDALQFETLDFDREDARKAGEI
RAALAILGTPIGAYNVLIAGQAVARDLILVTHNVREFQRVKNLRFEDWETV
VKYLLDSNAVIALMKGHSGFVAEIRKHKPQDFAIPAIVAHELFYGAYKGQRVADNLARVDALQFETLDFDREDARKAGEI
RAALAILGTPIGAYNVLIAGQAVARDLILVTHNVREFQRVKNLRFEDWETV
Download Length: 396 bp
>T151059 NZ_CP065199:1860144-1860239 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG
Antitoxin
Download Length: 81 a.a. Molecular weight: 9333.46 Da Isoelectric Point: 4.1849
>AT151059 WP_007702738.1 NZ_CP049213:c659725-659483 [Agrobacterium rhizogenes]
MDTAKIFWSGRSQAVRLPKEFRFDTDAVRIRRQGQAIILEPIVEDWDWLETVTGPVDQDFAEAATEQPVEQERPELDIFK
MDTAKIFWSGRSQAVRLPKEFRFDTDAVRIRRQGQAIILEPIVEDWDWLETVTGPVDQDFAEAATEQPVEQERPELDIFK
Download Length: 243 bp
>AT151059 NZ_CP065199:c1860324-1860267 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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