Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2701865..2702388 Replicon chromosome
Accession NZ_CP049206
Organism Agrobacterium rubi strain W2/73

Toxin (Protein)


Gene name parE Uniprot ID A0A1B9U0E5
Locus tag G6M88_RS12980 Protein ID WP_065698362.1
Coordinates 2701865..2702152 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A1B9U0D8
Locus tag G6M88_RS12985 Protein ID WP_065698361.1
Coordinates 2702149..2702388 (-) Length 80 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-91)

Antitoxin

(1-74)


Sequences


Toxin        


Download         Length: 96 a.a.        Molecular weight: 10702.29 Da        Isoelectric Point: 9.5632

>T151055 WP_065698362.1 NZ_CP049206:c2702152-2701865 [Agrobacterium rubi]
MKALLLTPKARSDIEGIWDYTVDNWGINQAEVYITAIQKALEGLADSSTISQSAESIRKNYRKTIVGSHTVFFKETNAAI
EVVRILHHRMSLARL

Download         Length: 288 bp

>T151055 NZ_CP065194:c1849059-1848955 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8850.88 Da        Isoelectric Point: 4.8550

>AT151055 WP_065698361.1 NZ_CP049206:c2702388-2702149 [Agrobacterium rubi]
MAKSTSVNLNDHFDAFIEQQIEDGRYASASEVLRAGLRLLEEREAELSHLRAALIEGEKSGDAVPFDFREFVRGKKNLG

Download         Length: 240 bp

>AT151055 NZ_CP065194:1848861-1848899 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A1B9U0E5


Antitoxin

Source ID Structure
AlphaFold DB A0A1B9U0D8

References