Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1066760..1067416 Replicon chromosome
Accession NZ_CP049206
Organism Agrobacterium rubi strain W2/73

Toxin (Protein)


Gene name vapC Uniprot ID A0A1B9T626
Locus tag G6M88_RS05205 Protein ID WP_065701614.1
Coordinates 1066760..1067122 (-) Length 121 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1B9T634
Locus tag G6M88_RS05210 Protein ID WP_065701615.1
Coordinates 1067159..1067416 (-) Length 86 a.a.

Genomic Context

G6M88_RS05180G6M88_RS05185G6M88_RS05195G6M88_RS05190G6M88_RS05200G6M88_RS05205G6M88_RS05210G6M88_RS05215
Location: 1062411..1063016 (606 bp)
Type: Others
Protein ID: WP_202032556.1
Location: 1063091..1063471 (381 bp)
Type: Others
Protein ID: WP_065701449.1
Location: 1064256..1065212 (957 bp)
Type: Others
Protein ID: WP_065701451.1
Location: 1063508..1064173 (666 bp)
Type: Others
Protein ID: WP_065701450.1
Location: 1065282..1066739 (1458 bp)
Type: Others
Protein ID: WP_065701452.1
Location: 1066760..1067122 (363 bp)
Type: Toxin
Protein ID: WP_065701614.1
Location: 1067159..1067416 (258 bp)
Type: Antitoxin
Protein ID: WP_065701615.1
Location: 1067473..1072212 (4740 bp)
Type: Others
Protein ID: WP_065701453.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
G6M88_RS05180 (G6M88_05180)1062411..1063016+606WP_202032556.1LysE family transporter-
G6M88_RS05185 (G6M88_05185)1063091..1063471+381WP_065701449.1transcriptional regulator-
G6M88_RS05190 (G6M88_05190)1063508..1064173-666WP_065701450.1DJ-1/PfpI family protein-
G6M88_RS05195 (G6M88_05195)1064256..1065212+957WP_065701451.1GlxA family transcriptional regulator-
G6M88_RS05200 (G6M88_05200)1065282..1066739-1458WP_065701452.1glutamate synthase subunit beta-
G6M88_RS05205 (G6M88_05205)1066760..1067122-363WP_065701614.1type II toxin-antitoxin system VapC family toxinToxin
G6M88_RS05210 (G6M88_05210)1067159..1067416-258WP_065701615.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
G6M88_RS05215 (G6M88_05215)1067473..1072212-4740WP_065701453.1glutamate synthase large subunit-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-111)

Antitoxin

SpoVT-AbrB domain

(12-58)


Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13444.67 Da        Isoelectric Point: 9.7874

>T151048 WP_065701614.1 NZ_CP049206:c1067122-1066760 [Agrobacterium rubi]
MMRNPQGKVFQRIAKVGEDAVLTSIIVSCEVRFGIEKRQSEKLAKRFSDVFGTLSVKRLDTTVEGHYAVIRTKLEAMGNP
IGQMDMLIAAHALALDAVVVTDNEREFSRVPGLKVENWLR

Download         Length: 363 bp

>T151048 NZ_CP065178:c4104065-4103178 [Pectobacterium quasiaquaticum]
ATGCTGAAGCAACAAATTCGCCAAATCGTCCAGTCAAACCCTGACTATGCCGCAGTGACACCCGTCATAGAAAAAGAGAT
CTTGCATCATGACATTATAGATGTGCTGATCAAACAGGGTGTCATGCAACGGTTAACGTTTATTGGCGGCACCTCATTAC
GAATGTGTTACAACAGTAGCAGGCTATCAGAAGACCTTGATTTCAATGGTGGTCATGATTTCAAGCCCTCAGCATTTGAG
GGGCTGGAATCCGAGATCCAAACCTATATTCAGAACAAGTATGAAACCGAAGTTTGGGTAAACAAACCTTCTGGCGAGCA
GCAAGGGGATACCGTTTCTTGGAAAATTAGTATCGTAAAAGAAGCGAATCGTCCTGATTTGCCACGGCAAAAAATGCATA
TTGATGTCTGTGCTATTCCATCATTTGATATTGAAAAGCGCCCGCTAATCAATCATTACGACATTGTTGTACCGACTGAA
GGGATCTTGGTTCCGGTACAATCGTTACAAGAAACACTAGCCGATAAGCTGATCGCGTTAGCGTATCGGGCAAGACGTAT
AAAGCCTCGTGATATCTGGGATATTGTTTGGATTAAGCAGCGCGGCATTGATCTATCCAAAACACTGGTTGAAAAGAAAC
TCACCGCCAGACACAAGCAAACAGATGACTTTCGACAGGCGCTATCTATTCAGTTAGCTAAGTTAATGTCGCAAGATGAA
GTCCGTGACGACTTTAATATGGAAATGAGCCGCTTTATCCCTAAGCAAATTAAAGAGAGAACCCTCGATAATCCCGAATA
TTGGGATTATGTTCAGAGAGAGGTACATGCCATCACGTCTGAGTTATTGAATGACGTAACACCAAAAAATCCATTTGATA
TGGGTTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9823.05 Da        Isoelectric Point: 3.9682

>AT151048 WP_065701615.1 NZ_CP049206:c1067416-1067159 [Agrobacterium rubi]
MNVVKIAQVFNNGRSRAIRIPKEFEFEADQVEISMNENGDLLVHPVKKRSLLELLASLEPLSEEDWMPEIEDYPPEPVDL
GWDED

Download         Length: 258 bp

>AT151048 NZ_CP065178:c4104618-4104094 [Pectobacterium quasiaquaticum]
ATGACTAAATCTGATGAGCTACTAAACGTATTTTCCAAAGCGGTGAACGCTGGCGGTGGCATTCATAGTGCAACAGAGCT
GGCTTTTATGCAGGGTGTGCCATGTGACTCAGCCTTTAGAAAGTTCCTAGCCGATTGCGTAAAGAGGGGGTTGCTAAGAC
GAGTGGTGAAAGGCTTCTATGAAAGTGTTATTACACCACCTGAGCCTGAGACTGCCATTTATAAAATCATCAAAAAGTTG
CGCAGTGGCGTATTGAACTACATCAGTTTAGAAAGCCAGCTCAGTCATACCGGTGATATTTCACAAGTGGTGATGGGTAG
AGTCACGGTAGTGACTAAAGGTCGAAGTGGTTGTTTTGATACGCCTTATGGCGTGATTGAGTTTACCCATACTAAAAAGC
CAGTCGAGCAAGTTGCACCTAATTTGTACTATGACCCTGACATTAAAATGTATCGCGCATACAAGGAACAAGCGATTGCA
GATCTAAAGCACTGCCAGCGCAATCTACATATGTTGGAGAGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1B9T626

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1B9T634

References