Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 4834917..4836436 Replicon chromosome
Accession NZ_CP049205
Organism Xanthomonas oryzae pv. oryzae strain K1

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag G6N84_RS22845 Protein ID WP_011259680.1
Coordinates 4835513..4836436 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag G6N84_RS22840 Protein ID WP_011409027.1
Coordinates 4834917..4835516 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6N84_RS22805 4830800..4831018 - 219 Protein_4349 DUF1788 domain-containing protein -
G6N84_RS22810 4830999..4831738 - 740 Protein_4350 DUF1819 family protein -
G6N84_RS22815 4831788..4832814 + 1027 WP_133264944.1 IS630 family transposase -
G6N84_RS22820 4832957..4833755 + 799 WP_113091170.1 IS5 family transposase -
G6N84_RS22825 4833742..4834230 - 489 WP_027703988.1 BrxE family protein -
G6N84_RS22830 4834262..4834582 - 321 WP_011259682.1 hypothetical protein -
G6N84_RS22840 4834917..4835516 + 600 WP_011409027.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
G6N84_RS22845 4835513..4836436 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
G6N84_RS22850 4836516..4836764 - 249 WP_033013473.1 hypothetical protein -
G6N84_RS22855 4836798..4837019 - 222 Protein_4358 hypothetical protein -
G6N84_RS22860 4837452..4837694 + 243 WP_011259679.1 hypothetical protein -
G6N84_RS22865 4838119..4838628 + 510 WP_011259678.1 hypothetical protein -
G6N84_RS22870 4838645..4839177 - 533 Protein_4361 methyltransferase domain-containing protein -
G6N84_RS22875 4839197..4840573 - 1377 Protein_4362 IS5 family transposase -
G6N84_RS22880 4840685..4840837 - 153 Protein_4363 SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T151044 WP_011259680.1 NZ_CP049205:4835513-4836436 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T151044 NZ_CP065178:3279727-3280032 [Pectobacterium quasiaquaticum]
ATGCAATTCATTGTTTATCAATACAAACGAACCAGCCACTACAAAATATTTGTCGATGTGCAAAGCGATATTGTCGAGAC
ACCCAAGCGGCGTATGGTCATCCCGCTTATCGAATCACATCACCTGTCTGAGAAAGTGAATAAAACGCTGTTCCCGCTGA
TTCGTATCAATGGGGAAGATTATCGGCTGATGACAACTGAACTATCGAGCGTTCCTGTTGAGGTCATTGGTGAAGAGATT
GCGGATCTTGGCGATTACGCGGATGAGATCAAGGATGCTATCAATCTTATGTTCTGGGGGATTTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT151044 WP_011409027.1 NZ_CP049205:4834917-4835516 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT151044 NZ_CP065178:3279506-3279724 [Pectobacterium quasiaquaticum]
ATGAAACACCGCGTCAGCGTTACCGTGGACAAAGACAGTTATCAGGTTCTGAGTGCTGCCGGAGTCAATATTTCTGGTCT
GGTGAATGATGCCATTGGCAAAGAAGCCCGTCGCATCAAAGCTGAAGCGTGGAAGAAGGAAAACCGCGAAGGGATGGAAG
AAGTCGCCCGATTTATCGCACAGAATGGCTCGTTTGCGGATGAAAACAGGAACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References