Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1064476..1064747 Replicon chromosome
Accession NZ_CP049198
Organism Escherichia coli strain E686

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1064606..1064709 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1064476..1064747 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6000_RS04995 1061031..1061693 - 663 WP_000944256.1 exodeoxyribonuclease X -
G6000_RS05000 1061717..1062373 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
G6000_RS05005 1062475..1062705 - 231 WP_000916763.1 DNA polymerase III subunit theta -
G6000_RS05010 1062844..1063218 + 375 WP_000204705.1 CopC domain-containing protein YobA -
G6000_RS05015 1063222..1064094 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
G6000_RS05020 1064107..1064448 + 342 WP_001520705.1 YebY family protein -
- 1064476..1064747 - 272 - - Antitoxin
- 1064606..1064709 + 104 - - Toxin
G6000_RS05025 1064844..1065500 + 657 WP_001520704.1 protein-serine/threonine phosphatase -
G6000_RS05030 1065501..1065692 - 192 WP_001296140.1 YebW family protein -
G6000_RS05035 1065797..1066033 - 237 WP_001295499.1 DUF1480 family protein -
G6000_RS05040 1066151..1067590 - 1440 WP_024166480.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T150956 NZ_CP049198:1064606-1064709 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT150956 NZ_CP049198:c1064747-1064476 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References