Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1359878..1360149 Replicon chromosome
Accession NZ_CP049197
Organism Escherichia coli strain E597

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1360008..1360111 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1359878..1360149 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6Z98_RS06345 1356433..1357095 - 663 WP_000944256.1 exodeoxyribonuclease X -
G6Z98_RS06350 1357119..1357775 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
G6Z98_RS06355 1357877..1358107 - 231 WP_000916763.1 DNA polymerase III subunit theta -
G6Z98_RS06360 1358246..1358620 + 375 WP_000204705.1 CopC domain-containing protein YobA -
G6Z98_RS06365 1358624..1359496 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
G6Z98_RS06370 1359509..1359850 + 342 WP_001520705.1 YebY family protein -
- 1359878..1360149 - 272 - - Antitoxin
- 1360008..1360111 + 104 - - Toxin
G6Z98_RS06375 1360246..1360902 + 657 WP_001520704.1 protein-serine/threonine phosphatase -
G6Z98_RS06380 1360903..1361094 - 192 WP_001296140.1 YebW family protein -
G6Z98_RS06385 1361199..1361435 - 237 WP_001295499.1 DUF1480 family protein -
G6Z98_RS06390 1361553..1362992 - 1440 WP_024166480.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T150928 NZ_CP049197:1360008-1360111 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT150928 NZ_CP049197:c1360149-1359878 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References