150888

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 3465785..3466488 Replicon chromosome
Accession NZ_CP049192
Organism Enterobacter hormaechei strain Y2152

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag G5577_RS16290 Protein ID WP_164474319.1
Coordinates 3466147..3466488 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag G5577_RS16285 Protein ID WP_164474320.1
Coordinates 3465785..3466126 (+) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G5577_RS16250 3460938..3461813 + 876 WP_164474326.1 GTPase family protein -
G5577_RS16255 3462057..3462773 + 717 WP_032689717.1 WYL domain-containing protein -
G5577_RS16260 3462809..3463261 + 453 WP_164474325.1 hypothetical protein -
G5577_RS16265 3463333..3463806 + 474 WP_164474324.1 hypothetical protein -
G5577_RS16270 3463927..3464748 + 822 WP_164474323.1 DUF945 domain-containing protein -
G5577_RS16275 3464779..3465219 + 441 WP_164474322.1 antirestriction protein -
G5577_RS16280 3465232..3465774 + 543 WP_164474321.1 DNA repair protein RadC -
G5577_RS16285 3465785..3466126 + 342 WP_164474320.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
G5577_RS16290 3466147..3466488 + 342 WP_164474319.1 TA system toxin CbtA family protein Toxin
G5577_RS16295 3466747..3467754 + 1008 WP_000528271.1 restriction endonuclease -
G5577_RS16300 3467938..3468804 - 867 WP_059370654.1 HNH endonuclease -
G5577_RS16305 3469105..3469572 + 468 WP_072203119.1 SymE family type I addiction module toxin -
G5577_RS16310 3469789..3470247 + 459 WP_045345955.1 hypothetical protein -
G5577_RS16315 3470241..3470573 + 333 WP_045345957.1 DUF1493 family protein -
G5577_RS16320 3470592..3471089 + 498 WP_023315311.1 type VI secretion system tube protein Hcp -
G5577_RS16325 3471140..3471487 - 348 WP_045345958.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island fosA - 3433047..3475558 42511


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-109)

Antitoxin

Antitoxin CbeA

(13-112)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12749.70 Da        Isoelectric Point: 9.0060

>T150888 WP_164474319.1 NZ_CP049192:3466147-3466488 [Enterobacter hormaechei]
MKTLPATTPQAATLCLSPVAVWQMLIARLLEQHYGLTLNDTPFSDETVIQEHIDAGISLADAVNFLVEKYGLVRIDRRGF
NWQEQSPYLRTVDILRARQATGLLKRNRISAAR

Download         Length: 342 bp

>T150888 NZ_CP065136:3162055-3162549 [Escherichia coli]
ATGATTCAGGCCCCCGAGCCACTCATGGCAAGGCATCAATTCACCTCTTTTTGCTCGGGAGTAGAAACGATGGATAACTG
GCTAAAGCAGAGAGCCCTAAAAAATCAGCTTGCCGGCGCATCACGTACATTTGTTAGCTGTGATACGTATAGCAACGTTT
TGGCATATTATTCGCTTGCTTCCAGCGCCGTTGAAACGTATGTCGCGACAGGACGATTTCGCCGAAATATGCCAGAACCG
ATCCCTGTTGTAGTACTTGGTCGTCTGGCAATAGATAAATCATTACAGGGTCAGGGCATCGGTCGTGCGATGGTCAGAGA
TGCCGGTCTACGAGTACTACAGGCGGCTGAAGTCATTGGTATTCGCGGAATGTTGGTCCATGCGTTATCAGACCAGGCCC
GTGAGTTTTATCTGCGAGTGGGGTTTGAACCATCGCCTGTCGATTCTATGATACTGATGGCAACATTGGCTGATTTGCAG
GAATGTCTTAAATAG

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12799.32 Da        Isoelectric Point: 5.0608

>AT150888 WP_164474320.1 NZ_CP049192:3465785-3466126 [Enterobacter hormaechei]
MKSTDSENDSFLQWGLNRNVTPCFGARLVQEGYRLHYLVDRASITGEFSNAESLKLDEVFPHFISQMESMLTTGEMNSRQ
AHCVTLYHNGFTCEADTLGSCGYVYIAVYPTQR

Download         Length: 342 bp

>AT150888 NZ_CP065136:3161765-3162058 [Escherichia coli]
ATGCCAGCAGCCAATAACATTCCAACCAGGCGCGAATCTTTAAATTTGCGCATAAAACCCGCAGAACGCGATCTTATTGA
CCGGGCCGCTAAAGCCCGAGGAAAAAATCGCACCGAATTTGTCCTTGAGGCCGCCAGAGCCGCAGCTGAAGAGGCGCTCA
TTGAGCAGAGAATTTTCAGGATCGATTCTGATGATTACCAGCTATTTTTGAATCGTCTGGATCAGCCCCCCGCGCCCAAT
GCTGCATTACGCAAAACCATGCAAACACCCGCGCCGTGGGAGCAAAAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References