Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 2108985..2109688 Replicon chromosome
Accession NZ_CP049188
Organism Enterobacter hormaechei strain Y323

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag G5C52_RS10000 Protein ID WP_164474319.1
Coordinates 2108985..2109326 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag G5C52_RS10005 Protein ID WP_164474320.1
Coordinates 2109347..2109688 (-) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G5C52_RS09965 2103986..2104333 + 348 WP_045345958.1 hypothetical protein -
G5C52_RS09970 2104384..2104881 - 498 WP_023315311.1 type VI secretion system tube protein Hcp -
G5C52_RS09975 2104900..2105232 - 333 WP_045345957.1 DUF1493 family protein -
G5C52_RS09980 2105226..2105684 - 459 WP_045345955.1 hypothetical protein -
G5C52_RS09985 2105901..2106368 - 468 WP_072203119.1 SymE family type I addiction module toxin -
G5C52_RS09990 2106669..2107535 + 867 WP_059370654.1 HNH endonuclease -
G5C52_RS09995 2107719..2108726 - 1008 WP_000528271.1 restriction endonuclease -
G5C52_RS10000 2108985..2109326 - 342 WP_164474319.1 TA system toxin CbtA family protein Toxin
G5C52_RS10005 2109347..2109688 - 342 WP_164474320.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
G5C52_RS10010 2109699..2110241 - 543 WP_164474321.1 DNA repair protein RadC -
G5C52_RS10015 2110254..2110694 - 441 WP_164474322.1 antirestriction protein -
G5C52_RS10020 2110725..2111546 - 822 WP_164474323.1 DUF945 domain-containing protein -
G5C52_RS10025 2111667..2112140 - 474 WP_164474324.1 hypothetical protein -
G5C52_RS10030 2112212..2112664 - 453 WP_164474325.1 hypothetical protein -
G5C52_RS10035 2112700..2113416 - 717 WP_032689717.1 WYL domain-containing protein -
G5C52_RS10040 2113660..2114535 - 876 WP_164474326.1 GTPase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-109)

Antitoxin

Antitoxin CbeA

(13-112)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12749.70 Da        Isoelectric Point: 9.0060

>T150860 WP_164474319.1 NZ_CP049188:c2109326-2108985 [Enterobacter hormaechei]
MKTLPATTPQAATLCLSPVAVWQMLIARLLEQHYGLTLNDTPFSDETVIQEHIDAGISLADAVNFLVEKYGLVRIDRRGF
NWQEQSPYLRTVDILRARQATGLLKRNRISAAR

Download         Length: 342 bp

>T150860 NZ_CP065053:c2482064-2481555 [Massilia sp. CCM 8941]
ATGATTCTTACCCCGCTCAACGCTGTTGCCTACCGGGTCCACCAGCCGAAATGGTCATTTGCGCCGACCTCGGGGGCCGG
TGCCGGCGCCTATGGCGGGCGCGCCAACCGGCCTGGTGTCAATGCGCTCTACCTGTCACTGGAGCTGGAGACCGCCCTAG
CCGAGTACCAGCAGCTCGATGCGCTCCTGCCGCCCGGGCTCATGGTCAGCTATAACGTAAGCATCAACGCCATCGTGGAC
TTCCGCGGCGGCTTTACCAGCGGCTGGGACGCGCTCTGGCAAGATTTTTACTGCGACTGGCGGAACATGCATTTCAACCA
AGGCATTGAACCCCCATCCTGGGTCATCGGCGATCAGGTCCTTGCTGCCGACGCAAAGGGAATCCTGTTCAATTCCGCGA
TCACCGGCGGAGAGAATCTTGTCATCTACACTGACGCGCTGACCGGCGCCGATGCCATCAACGTCTACGATCCGAACAAC
GATCTCCCAAAGAACCAATCGTCCTGGTAA

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12799.32 Da        Isoelectric Point: 5.0608

>AT150860 WP_164474320.1 NZ_CP049188:c2109688-2109347 [Enterobacter hormaechei]
MKSTDSENDSFLQWGLNRNVTPCFGARLVQEGYRLHYLVDRASITGEFSNAESLKLDEVFPHFISQMESMLTTGEMNSRQ
AHCVTLYHNGFTCEADTLGSCGYVYIAVYPTQR

Download         Length: 342 bp

>AT150860 NZ_CP065053:c2482462-2482061 [Massilia sp. CCM 8941]
ATGACCGTCCCTGCCGGCGAGGCAGTTCCTGTATTCGATCGCAACTTCGACGAATTCATGAATTTCCTCAATTCCGAGGC
GAGCCCGTCGATTTCCCCAAAACGATTCGGACTTGTTTTCAGGGTAGATATGCAGACGCTCGCGGCGCAGGCACACGTTC
ACAGGAACACCGTCAGGCTGGCACCGGACACCGAGACCATCCAGTCGTACCTGCGTGAATCGGTGCGCGTGATGTGCGCT
GCCACCGATATTAGCGGCAGCATCGAAAAAGCGATCTACTGGTTCAAGAATCATCCACTGCCGACATTCGACTACAAGAC
GCCCCAGGACCTCGTTTCAGAAAAACGCACAGACGCTCTCATCAAGTACATCCAGTCGCTACAAGCCGGGTACATCGGAT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References