Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4210563..4210797 | Replicon | chromosome |
| Accession | NZ_CP049179 | ||
| Organism | Shigella sonnei strain L4094 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4210564..4210667 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4210563..4210797 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| G6O64_RS21225 | 4205697..4206852 | - | 1156 | Protein_4139 | IS3-like element IS600 family transposase | - |
| G6O64_RS21230 | 4206997..4207257 | + | 261 | WP_077447296.1 | excisionase | - |
| G6O64_RS21235 | 4207286..4207740 | + | 455 | Protein_4141 | IS1-like element IS1A family transposase | - |
| G6O64_RS21240 | 4207835..4209063 | + | 1229 | WP_088895425.1 | IS3-like element IS2 family transposase | - |
| G6O64_RS21245 | 4209074..4209319 | + | 246 | Protein_4143 | IS1 family transposase | - |
| G6O64_RS21250 | 4209356..4210432 | + | 1077 | WP_052987259.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 4210563..4210797 | + | 235 | - | - | Antitoxin |
| - | 4210564..4210667 | - | 104 | - | - | Toxin |
| G6O64_RS21255 | 4210825..4211166 | - | 342 | WP_000976476.1 | YebY family protein | - |
| G6O64_RS21260 | 4211179..4212051 | - | 873 | WP_000879296.1 | copper homeostasis membrane protein CopD | - |
| G6O64_RS21265 | 4212055..4212429 | - | 375 | WP_000168735.1 | CopC domain-containing protein YobA | - |
| G6O64_RS21270 | 4212568..4212798 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| G6O64_RS21275 | 4212900..4213556 | + | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein YobB | - |
| G6O64_RS21280 | 4213580..4214242 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 4183603..4218207 | 34604 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T150823 NZ_CP049179:c4210667-4210564 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT150823 NZ_CP049179:4210563-4210797 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
