Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1824433..1824667 Replicon chromosome
Accession NZ_CP049177
Organism Shigella sonnei strain 1205.3131

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1824563..1824666 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1824433..1824667 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6O63_RS09040 1820988..1821650 - 663 WP_000944256.1 exodeoxyribonuclease X -
G6O63_RS09045 1821674..1822330 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
G6O63_RS09050 1822432..1822662 - 231 WP_000916763.1 DNA polymerase III subunit theta -
G6O63_RS09055 1822801..1823175 + 375 WP_000168735.1 CopC domain-containing protein YobA -
G6O63_RS09060 1823179..1824051 + 873 WP_000879296.1 copper homeostasis membrane protein CopD -
G6O63_RS09065 1824064..1824405 + 342 WP_000976476.1 YebY family protein -
- 1824433..1824667 - 235 - - Antitoxin
- 1824563..1824666 + 104 - - Toxin
G6O63_RS09070 1824798..1825874 - 1077 WP_052987259.1 phage integrase Arm DNA-binding domain-containing protein -
G6O63_RS09075 1825911..1826156 - 246 Protein_1763 IS1 family transposase -
G6O63_RS09085 1827490..1827944 - 455 Protein_1765 IS1-like element IS1A family transposase -
G6O63_RS09090 1827973..1828233 - 261 WP_077447296.1 excisionase -
G6O63_RS09095 1828378..1829533 + 1156 Protein_1767 IS3-like element IS600 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - ipaH9.8 1818931..1851627 32696


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T150794 NZ_CP049177:1824563-1824666 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT150794 NZ_CP049177:c1824667-1824433 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References