Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1574107..1574341 Replicon chromosome
Accession NZ_CP049173
Organism Shigella sonnei strain 19.0820.1561

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1574108..1574211 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1574107..1574341 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6O61_RS08180 1570482..1571237 + 756 WP_001282649.1 IS21-like element ISSso4 family helper ATPase IstB -
G6O61_RS08185 1571379..1572607 + 1229 WP_088895425.1 IS3-like element IS2 family transposase -
G6O61_RS08190 1572618..1572863 + 246 Protein_1601 IS1 family transposase -
G6O61_RS08195 1572900..1573976 + 1077 WP_001189101.1 phage integrase Arm DNA-binding domain-containing protein -
- 1574107..1574341 + 235 - - Antitoxin
- 1574108..1574211 - 104 - - Toxin
G6O61_RS08200 1574369..1574710 - 342 WP_000976476.1 YebY family protein -
G6O61_RS08205 1574723..1575595 - 873 WP_000879296.1 copper homeostasis membrane protein CopD -
G6O61_RS08210 1575599..1575973 - 375 WP_000168735.1 CopC domain-containing protein YobA -
G6O61_RS08215 1576112..1576342 + 231 WP_000916763.1 DNA polymerase III subunit theta -
G6O61_RS08220 1576444..1577100 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
G6O61_RS08225 1577124..1577786 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - ipaH9.8 / ipaH9.8 1560062..1580881 20819


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T150749 NZ_CP049173:c1574211-1574108 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT150749 NZ_CP049173:1574107-1574341 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References