Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4018843..4019077 | Replicon | chromosome |
| Accession | NZ_CP049169 | ||
| Organism | Shigella sonnei strain 19.1125.3493 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4018844..4018947 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4018843..4019077 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| G6O58_RS20125 | 4013986..4015141 | - | 1156 | Protein_3918 | IS3 family transposase | - |
| G6O58_RS20130 | 4015286..4015546 | + | 261 | WP_077447296.1 | excisionase | - |
| G6O58_RS20135 | 4015575..4016029 | + | 455 | Protein_3920 | IS1-like element IS1A family transposase | - |
| G6O58_RS20140 | 4016124..4017353 | + | 1230 | WP_086558215.1 | IS3-like element IS2 family transposase | - |
| G6O58_RS20145 | 4017364..4017609 | + | 246 | Protein_3922 | IS1 family transposase | - |
| G6O58_RS20150 | 4017646..4018722 | + | 1077 | WP_001189101.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 4018843..4019077 | + | 235 | - | - | Antitoxin |
| - | 4018844..4018947 | - | 104 | - | - | Toxin |
| G6O58_RS20155 | 4019105..4019446 | - | 342 | WP_000976476.1 | YebY family protein | - |
| G6O58_RS20160 | 4019459..4020331 | - | 873 | WP_000879296.1 | copper homeostasis membrane protein CopD | - |
| G6O58_RS20165 | 4020335..4020709 | - | 375 | WP_000168735.1 | CopC domain-containing protein YobA | - |
| G6O58_RS20170 | 4020848..4021078 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| G6O58_RS20175 | 4021180..4021836 | + | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein YobB | - |
| G6O58_RS20180 | 4021860..4022522 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 / ipaH9.8 | 3991896..4082459 | 90563 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T150717 NZ_CP049169:c4018947-4018844 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT150717 NZ_CP049169:4018843-4019077 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
