Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2536341..2536510 Replicon chromosome
Accession NZ_CP049154
Organism Cronobacter sakazakii strain C105731

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2536345..2536448 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2536341..2536510 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G4U59_RS11765 (G4U59_11720) 2531540..2531779 + 240 WP_004386676.1 YebV family protein -
G4U59_RS11770 (G4U59_11725) 2531904..2532095 + 192 WP_004386675.1 YebW family protein -
G4U59_RS11775 (G4U59_11730) 2532096..2532740 - 645 WP_105944385.1 metallophosphoesterase -
G4U59_RS11785 2533098..2533190 - 93 WP_012124476.1 hypothetical protein -
G4U59_RS11790 (G4U59_11735) 2533536..2533871 - 336 WP_004386671.1 hypothetical protein -
G4U59_RS11795 (G4U59_11740) 2534069..2535238 - 1170 WP_216295942.1 acyltransferase -
G4U59_RS11800 (G4U59_11745) 2535235..2535489 - 255 WP_134871580.1 hypothetical protein -
G4U59_RS11805 (G4U59_11750) 2535929..2536204 - 276 WP_105944387.1 hypothetical protein -
- 2536341..2536510 + 170 - - Antitoxin
- 2536345..2536448 - 104 - - Toxin
G4U59_RS11810 (G4U59_11755) 2536587..2536925 - 339 WP_004386669.1 YebY family protein -
G4U59_RS11815 (G4U59_11760) 2536940..2537809 - 870 WP_216295943.1 copper homeostasis membrane protein CopD -
G4U59_RS11820 (G4U59_11765) 2537814..2538188 - 375 WP_007868632.1 CopC domain-containing protein YobA -
G4U59_RS11825 (G4U59_11770) 2538335..2538565 + 231 WP_104658196.1 DNA polymerase III subunit theta -
G4U59_RS11830 (G4U59_11775) 2538638..2539300 + 663 WP_007775901.1 exodeoxyribonuclease X -
G4U59_RS11835 (G4U59_11780) 2539297..2541360 - 2064 WP_105944809.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T150634 NZ_CP049154:c2536448-2536345 [Cronobacter sakazakii]
GGCAAGGCGACTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 170 bp

>AT150634 NZ_CP049154:2536341-2536510 [Cronobacter sakazakii]
AGATAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTCAGTCGCCTTGCCTTTTAAGAATAGATGACGACACCAGCTTTTCCAGTTTGCGGCTAAAGTCGCA
GCAAAAAGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References