Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3923752..3923920 Replicon chromosome
Accession NZ_CP049144
Organism Cronobacter sakazakii strain C79

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3923755..3923858 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3923752..3923920 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G4U62_RS18570 (G4U62_18540) 3919125..3920567 + 1443 WP_148736170.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
G4U62_RS18575 (G4U62_18545) 3920680..3920919 + 240 WP_148736169.1 YebV family protein -
G4U62_RS18580 (G4U62_18550) 3921044..3921235 + 192 WP_004386675.1 YebW family protein -
G4U62_RS18585 (G4U62_18555) 3921236..3921880 - 645 WP_148736168.1 metallophosphoesterase -
G4U62_RS18590 3922239..3922331 - 93 WP_004386672.1 hypothetical protein -
G4U62_RS18595 (G4U62_18560) 3922677..3923012 - 336 WP_004386671.1 hypothetical protein -
G4U62_RS18600 (G4U62_18565) 3922966..3923526 - 561 WP_032968251.1 hypothetical protein -
- 3923752..3923920 + 169 - - Antitoxin
- 3923755..3923858 - 104 - - Toxin
G4U62_RS18605 (G4U62_18570) 3923997..3924335 - 339 WP_012124470.1 YebY family protein -
G4U62_RS18610 (G4U62_18575) 3924350..3925219 - 870 WP_148736167.1 copper homeostasis membrane protein CopD -
G4U62_RS18615 (G4U62_18580) 3925224..3925598 - 375 WP_148736166.1 CopC domain-containing protein YobA -
G4U62_RS18620 (G4U62_18585) 3925745..3925975 + 231 WP_104658196.1 DNA polymerase III subunit theta -
G4U62_RS18625 (G4U62_18590) 3926048..3926710 + 663 WP_007775901.1 exodeoxyribonuclease X -
G4U62_RS18630 (G4U62_18595) 3926707..3928770 - 2064 WP_148736165.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T150622 NZ_CP049144:c3923858-3923755 [Cronobacter sakazakii]
GGCAAGGCGACTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 169 bp

>AT150622 NZ_CP049144:3923752-3923920 [Cronobacter sakazakii]
GATAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGG
CATTAATGCAGGCTCAGTCGCCTTGCCTTTTAAGAATAGATGACGACACCAGCTTTTCCAGTTTGCGGCTAAAGTCGCAG
CAAAAAGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References