150527

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1958534..1958805 Replicon chromosome
Accession NZ_CP049110
Organism Escherichia coli strain WF5-5-T1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1958664..1958767 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1958534..1958805 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G5631_RS09430 1955089..1955751 - 663 WP_000944256.1 exodeoxyribonuclease X -
G5631_RS09435 1955775..1956431 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
G5631_RS09440 1956533..1956763 - 231 WP_000916763.1 DNA polymerase III subunit theta -
G5631_RS09445 1956902..1957276 + 375 WP_000168747.1 CopC domain-containing protein YobA -
G5631_RS09450 1957280..1958152 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
G5631_RS09455 1958165..1958506 + 342 WP_000976476.1 YebY family protein -
- 1958534..1958805 - 272 - - Antitoxin
- 1958664..1958767 + 104 - - Toxin
G5631_RS09460 1958902..1959558 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
G5631_RS09465 1959559..1959750 - 192 WP_000457842.1 YebW family protein -
G5631_RS09470 1959855..1960091 - 237 WP_001295499.1 YebV family protein -
G5631_RS09475 1960209..1961648 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T150527 NZ_CP049110:1958664-1958767 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT150527 NZ_CP049110:c1958805-1958534 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References