Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relE/YoeB-RelB
Location 3477252..3477769 Replicon chromosome
Accession NZ_CP049107
Organism Sphingomonas sp. MK52

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag G6P88_RS16225 Protein ID WP_165324104.1
Coordinates 3477503..3477769 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag G6P88_RS16220 Protein ID WP_165324103.1
Coordinates 3477252..3477506 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6P88_RS16200 3472257..3474482 + 2226 WP_165324099.1 TonB-dependent receptor -
G6P88_RS16205 3474553..3474999 + 447 WP_165324100.1 nuclear transport factor 2 family protein -
G6P88_RS16210 3475022..3476359 + 1338 WP_165324101.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
G6P88_RS16215 3476385..3477131 + 747 WP_165324102.1 SDR family oxidoreductase -
G6P88_RS16220 3477252..3477506 + 255 WP_165324103.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
G6P88_RS16225 3477503..3477769 + 267 WP_165324104.1 Txe/YoeB family addiction module toxin Toxin
G6P88_RS16230 3477959..3479119 + 1161 WP_206335792.1 DDE-type integrase/transposase/recombinase -
G6P88_RS16240 3479417..3480313 + 897 WP_165325247.1 tetratricopeptide repeat protein -
G6P88_RS16245 3480325..3480939 + 615 WP_165324106.1 LON peptidase substrate-binding domain-containing protein -
G6P88_RS16250 3480936..3481103 + 168 WP_165324107.1 Trm112 family protein -
G6P88_RS16255 3481149..3482369 - 1221 WP_165325248.1 FAD-dependent monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10315.74 Da        Isoelectric Point: 8.5042

>T150513 WP_165324104.1 NZ_CP049107:3477503-3477769 [Sphingomonas sp. MK52]
MKLVFADAAWDDYLHWQANAPNTLQRVNDLIKECQRSPFKGTGKPEPLKGDLKGWWSRRITLEDRLVYRVTGSPPDQQLE
IAQCRFHY

Download         Length: 267 bp

>T150513 NZ_CP064761:c1329958-1329695 [Companilactobacillus futsaii]
ATGAAAATTGATCGAGTAAGTTTTACCATTAAGGCTTTGTCAGATTATCAATATTGGCAAAAACAAGACCGAAAAACTTT
AAAGATTCTAAATCGAATAATTAATGATATTATTCGACATCCCTTTACGGGTATAGGTAAACCGGAACCTTTAAAATACA
AATTAGACAATTGCTGGTCCAGAAGAATTAATAAAAGCGACCGAATCGTCTATACGGTTACAAATGATTCAATCATTATC
ATTCAATGTCGCTATCATTACTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9320.60 Da        Isoelectric Point: 4.7914

>AT150513 WP_165324103.1 NZ_CP049107:3477252-3477506 [Sphingomonas sp. MK52]
MDVISYSDTRAHLKEVMDRVVADRAPIVVSRQKAESVVMVSLSDWNAIEESMHLLSTEANRGRLLAAIQQLDSGKGEARD
LIEP

Download         Length: 255 bp

>AT150513 NZ_CP064761:c1330229-1329948 [Companilactobacillus futsaii]
ATGGCAACTACCGCAACTAACATTTCTGAAGCAAGAAAGAATTTAAAAAAATTAACTGACGACGTAGTTGATTATGATGA
TCATGTAATAATTACGAAGCCAAAAAATCGTAATGTGGTTATTATGTCGGAAAAAGAATATCAATCTTGGAAAGAAACCA
TGTACCTACTCGGCACAGAAGCAAATCGTAAAAATTTGGATGAATCTTTAGAGCAACTAAACAGAGGTAACCTAAAGACA
ATATCAAAAGAAGAATGGGATAAACTTTCTAATGAAAATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References