Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 970441..971212 Replicon chromosome
Accession NZ_CP049091
Organism Staphylococcus haemolyticus strain SE3.9

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag RES7_RS04855 Protein ID WP_141738627.1
Coordinates 971063..971212 (+) Length 50 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag RES7_RS04850 Protein ID WP_161511415.1
Coordinates 970441..971040 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RES7_RS04830 (RES7_004830) 966315..967769 + 1455 WP_161511412.1 ABC transporter substrate-binding protein/permease -
RES7_RS04835 (RES7_004835) 967762..968484 + 723 WP_161511413.1 amino acid ABC transporter ATP-binding protein -
RES7_RS04840 (RES7_004840) 968671..969798 + 1128 WP_161511414.1 tRNA epoxyqueuosine(34) reductase QueG -
RES7_RS04845 (RES7_004845) 969799..970269 + 471 WP_053025428.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
RES7_RS04850 (RES7_004850) 970441..971040 + 600 WP_161511415.1 glucosamine-6-phosphate isomerase Antitoxin
RES7_RS04855 971063..971212 + 150 WP_141738627.1 SAS053 family protein Toxin
RES7_RS04860 (RES7_004855) 971422..971817 + 396 WP_161511416.1 hypothetical protein -
RES7_RS04865 (RES7_004860) 972022..973407 + 1386 WP_161511417.1 class II fumarate hydratase -
RES7_RS04870 (RES7_004865) 973473..974297 - 825 WP_085060648.1 RluA family pseudouridine synthase -
RES7_RS04875 (RES7_004870) 974485..975594 + 1110 WP_161511418.1 GAF domain-containing sensor histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(130-195)


Sequences

Toxin        


Download         Length: 50 a.a.        Molecular weight: 5824.20 Da        Isoelectric Point: 3.9484

>T150474 WP_141738627.1 NZ_CP049091:971063-971212 [Staphylococcus haemolyticus]
MTKNKDSELNYHEEENAMVQDLDDLKTLGKEMEQISEENDEDRLNQSHE

Download         Length: 150 bp

>T150474 NZ_CP064689:c4778896-4778462 [Bradyrhizobium sp. 200]
GTGTACCTCGTCGACACCAACATCATTTCAAGCGCGGCGCCCGGGCGGCCGGCACCATCTGCGCTTGTCGAATGGATGGA
TGTGCATTCCGCTTCGCTGTTCCTATCCGTGGTGACTGTCGCCGAGATCGAAGACGGAATCGCCAAATTGATGCGCGAGG
GAGCGACGCGCAAGAGTGCGGATCTGGCATCATGGTTGGAAACAGTGTTGCATCTCTACGGTCAGCGAATTCTTGTTTTC
GATGCACCCACCGCACGGATCGCCGGTGGCGTCGCCGATCAGGCGCGGGGAAGAGGTCATGCGCCCGGCTTTGCCGACAT
CATCATCGCGGCGACAGCCCGGCGTCACGAACTCACAATTCTGTCGCGCAATGTTAGGCATTTCGAGCCGCTCGGTGTTC
CTGTGCTCGATCCCTTCACGACCTTGCCATCGTAG

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22256.12 Da        Isoelectric Point: 4.7588

>AT150474 WP_161511415.1 NZ_CP049091:970441-971040 [Staphylococcus haemolyticus]
MAMNFKVFNDVEHVAEYTADIIRKQFNNNPTTIAGIHLTKDAAPVLDELKKDVDHNAVDFSQVNILDYDDNRSYYEALGV
PASQIYPINLDDDAESLIDDKIKTKENKGKLILQVTSIDESGSLNVNVRQGLLKAREVVLVVTGANKREVVKKLYEENGK
SSFEPADLKAHRMVTVVLDRAAAEGLPEDVKEYFTARFA

Download         Length: 600 bp

>AT150474 NZ_CP064689:c4779146-4778904 [Bradyrhizobium sp. 200]
ATGAAAGAAATTCAGCTTCGAGATGCAAAGGCTAGCCTGTCTGCCGTGGTCGACGAGGCGATGCGTGGGAAGCCTGCGGT
CATTACCCGACACGGTAAACGGCAGGCAGTGGTCGTCAGCTACGAGGAGTGGGAGCGACTATCCCACGTTCCGACTTTCG
GCCGACTGCTGATGGCGGCTCCATTGGTGGCGGACGATCTGCCAAACCGCAACAGTTCTGGTCCGCGCACTGCTGATCTC
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References