Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2296710..2296978 Replicon chromosome
Accession NZ_CP049077
Organism Escherichia coli strain p11A

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2296838..2296940 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2296710..2296978 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6P89_RS11160 2293263..2293925 - 663 WP_000944256.1 exodeoxyribonuclease X -
G6P89_RS11165 2293949..2294605 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
G6P89_RS11170 2294707..2294937 - 231 WP_000916763.1 DNA polymerase III subunit theta -
G6P89_RS11175 2295076..2295450 + 375 WP_000168747.1 CopC domain-containing protein YobA -
G6P89_RS11180 2295454..2296326 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
G6P89_RS11185 2296339..2296680 + 342 WP_000976472.1 YebY family protein -
- 2296710..2296978 - 269 - - Antitoxin
- 2296838..2296940 + 103 - - Toxin
G6P89_RS11190 2297075..2297731 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
G6P89_RS11195 2297732..2297923 - 192 WP_001296140.1 YebW family protein -
G6P89_RS11200 2298028..2298264 - 237 WP_001295499.1 DUF1480 family protein -
G6P89_RS11205 2298381..2299820 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2216163..2312817 96654


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T150357 NZ_CP049077:2296838-2296940 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT150357 NZ_CP049077:c2296978-2296710 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References